Birth Defects Surveillance Toolkit

Congenital Infectious Syndrome

Infant with typical cloudiness of the eye lenses; that is, cataracts, in a case of CRS

Congenital glaucoma (and cataract) in a 7-month-old infant with CRS. The left eye displays a congenital cataract; the right eye is normal. The infant was operated on on day 3 of life to correct the congenital cataract.

Infant with congenital rubella and “blueberry muffin” skin lesions.

Congenital Rubella Syndrome

Congenital Syphilis

mucopurulent discharge

Congenital Cytomegalovirus

blueberry muffin rash

Lateral views showing collapse of the cranium and extreme reduction in height of the cranial vault.

Posterior scalp view showing redundant scalp with folds (rugae).

Computed tomographic (CT) scan

Magnetic resonance imaging (MRI) in infant with prenatal Zika exposure shows scattered punctate calcifications

Newborn infant with bilateral contractures of the hips and knees, bilateral talipes calcaneovalgus, and anterior dislocation of the knees.

Fundus images of right and left eye: Optic nerve hypoplasia with the double-ring sign, gross pigmentary mottling, and chorioretinal scar in the macular region.

Page last reviewed: January 22, 2021

Content source: Division of Birth Defects and Developmental Disabilities, NCBDDD, Centers for Disease Control and Prevention

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