Treatment for Aspergillosis

Allergic forms of aspergillosis

For allergic forms of aspergillosis such as allergic bronchopulmonary aspergillosis (ABPA) or allergic Aspergillus sinusitis, the recommended treatment is itraconazole, a prescription antifungal medication. Corticosteroids may also be helpful.

Invasive aspergillosis

Invasive aspergillosis needs to be treated with prescription antifungal medication, usually voriconazole. Other antifungal medications used to treat aspergillosis include lipid amphotericin formulations, posaconazole, isavuconazole, itraconazole, caspofungin, and micafungin. Whenever possible, immunosuppressive medications should be discontinued or decreased. People who have severe cases of aspergillosis may need surgery. Other invasive forms of aspergillosis such as chronic pulmonary aspergillosis and cutaneous aspergillosis should be treated similarly to invasive aspergillosis. Aspergillomas (“fungus ball”) might not need treatment.

If you are a healthcare provider, click here to see the Infectious Diseases Society of America’s Practice Guidelines for the Diagnosis and Management of AspergillosisExternal.

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