Global Fungal Disease Surveillance and Capacity Funding Opportunity

NOFO: CK21-2106

Global NOFO Webinar

The purpose of this Notice of Funding Opportunity (NOFO) is to reduce illness and death due to fungal diseases around the world caused by both known and emerging pathogens. This internationally focused NOFO supports CDC’s strategic priorities to prevent the spread of infectious diseases.

Globally, fungal diseases pose a significant public health threat, and can be:

  • Opportunistic, meaning they affect people with weakened immune systems, for example, people living with HIV/AIDS.
  • Acquired in the community or in healthcare settings.
  • Resistant to antifungal drugs, making treatment challenging.

CDC’s Mycotic Diseases Branch works throughout the world to prevent and control fungal infections. This includes improving diagnosis and treatment of cryptococcal meningitis and histoplasmosis, especially in people living with HIV/AIDS, and responding to emerging fungal diseases such as Candida auris, which causes severe illness in hospitalized patients.

This NOFO prioritizes:

Millions of fungal diseases around the world
  1. Increasing surveillance for fungal diseases and outbreaks by building epidemiology, laboratory, and bioinformatics capacity
  2. Increasing support for identifying and responding to known, reemerging, and new fungal pathogens
  3. Engaging and training frontline personnel and broader workforce in CDC best practices to support the prevention and control of fungal diseases
  4. Targeting guidance and tools to:
    1. Better reach communities and populations at increased risk for fungal diseases
    2. Reduce fungal disease spread in health care facilities or high-risk settings
  5. Monitoring and evaluating the impact and effectiveness of strategies for improved fungal infection prevention and control practices
  6. Assessing and refining performance metrics for:
    1. Fungal infection control and prevention practices
    2. Outbreak data
    3. Fungal identification strategies
    4. Antifungal resistant specimens
    5. Strain-typing strategies (e.g., whole genome sequencing)

Project proposals should demonstrate direct public health impact through prevention and control of fungal diseases. Priority populations will vary depending on the activities or specific fungal disease.

How to Apply

This NOFO is forecasted on Grants.govexternal icon. More information about this NOFO, and how to apply, will be updated in the coming months on

For questions about the NOFO, please email