Leading Progress in Ending the Global HIV Epidemic

More than four decades since the first cases were reported, HIV is still a leading cause of death and a health threat to millions worldwide. While innovations in HIV care, treatment, and prevention now help people with HIV to enjoy longer, healthier lives, many people are not benefiting from the latest scientific advances, mainly due to stigma and discrimination. Strong partnerships, dedication to eliminating stigma and discrimination, and ensuring equitable access to quality, people-centered HIV services, remain central to sustaining progress and ending HIV as an epidemic. This requires the equitable use of effective treatment and prevention programs focusing on populations disproportionately impacted by HIV.

As a key implementing partner of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), CDC works side-by-side with ministries of health, civil and faith-based organizations, private sector organizations, and other on-the-ground partners to improve methods for finding, treating, and preventing HIV. The investments made today in response to HIV will save lives, strengthen communities, and pave the way for long-term sustainability.

CDC Global HIV & TB Research at CROI 2023

CDC On The Frontlines - Global HIV

The annual Conference on Retroviruses and Opportunistic Infections (CROI) is being held from February 19-22, 2023, in Seattle, Washington. This conference brings together top basic, translational, and clinical researchers from around the world to highlight the most significant original research on HIV and related infectious diseases.

For 20 years, PEPFAR has led progress towards ending the HIV epidemic by supporting treatment and prevention efforts in more than 50 countries. As a leading implementer of PEPFAR, CDC has played a critical role, bringing its scientific and technical expertise to bear in the fight against HIV and leading cutting-edge research to advance the global HIV response.

This year, CDC’s global experts will present 17 poster abstracts at CROI, highlighting their latest work to accelerate global progress towards ending HIV. Key CDC research presented at CROI 2023 will include studies highlighting efforts to address critical gaps in reaching populations that continue to be left behind, including children and women. Several other CDC studies will highlight our work supporting country partners to expand the reach of lifesaving anti-retroviral therapy and TB preventive treatment to people living with HIV.

View the full list of CDC’s global HIV and TB research at CROI below.

Tracking Impact

CDC On The Frontlines - Global HIV
The Population-Based HIV Impact Assessments (PHIAs) surveys are an important tool for measuring the impact of HIV treatment and prevention programs in PEPFAR-supported countries. CDC and partners apply analytical insights from PHIAs to make timely adjustments to programs, leading to increased efficiencies and positive outcomes for community members, including people living with HIV. Learn more about PHIAs and the countries where surveys have been completed.

Latest Research

Latest research from CDC on global HIV and TB.


An overview of CDC’s global efforts in response to one of the world’s greatest health threats.

DGHT overview resource-cover
CDC’s role in the global HIV response.
CDC’s fight against global HIV.
Ped AIDS Factsheet
Addressing HIV in Children.