Global TB Overview


Two billion people – one fourth of the world’s population – may be infected with tuberculosis (TB), with 10.6 million becoming ill each year. Despite being preventable and treatable, TB remains a deadly disease. Globally, over 3,500 people lose their lives to TB each day – totaling 1.3 million deaths each year. Additionally, around 30 percent of people who become ill with TB are missed by healthcare screenings and diagnostics and do not get the care they need, leading to poor health outcomes and an increased spread of TB in communities. Each of these untreated people can infect 10 to 15 additional people per year – and 10% of those infected go on to develop active TB in their lifetimes.

CDC and partners are working on the frontlines in the world’s highest TB and TB/HIV burden countries to understand what’s driving the spread of TB and how to stop it. To make progress – and find the missing millions who do not receive the healthcare needed – we must address the drivers of this epidemic in the most at-risk populations and increase access to TB preventive measures. By taking immediate and effective action, we can change the course of the epidemic and finally make TB history.

CDC’s Contributions

With unmatched scientific and technical knowledge and long-standing relationships with ministries of health, CDC is on the frontlines in 42 high TB or TB/HIV burden countries to prevent, find, and cure TB.

CDC and partners identify TB hotspots for targeted screening, strengthen infection control practices in health facilities and communities, and scale treatment to prevent TB among vulnerable populations. With the strategic use of data, CDC is able to help partners increase impact and cost-effectiveness – all while saving lives.

CDC provides a proven track record in strengthening laboratories and surveillance systems. Through robust partnerships, CDC is expanding access to better screening, improving case-finding approaches to identify new patients, enhancing testing strategies to optimize diagnostics, and providing training and technical support to scale faster diagnostic tools.

CDC’s cadre of global and domestic experts inform U.S. and global efforts in the TB response. By working closely with ministries of health, CDC is able to help implement high-quality treatment programs, broaden access and improve linkage to care, assess costs to patients, optimize and evaluate TB and drug-resistant TB treatment regimens, and improve treatment adherence.

CDC’s experience building large and sustainable TB and public health programs is unparalleled. Through strategic and on-going partnerships, CDC works to develop and strengthen surveillance and laboratory systems; expands workforce and research capacity through guidelines mentorship, and training programs; strengthen programs through operational research, implementation, and evaluation.

CDC’s Contributions to Ending HIV-Associated TB

TB remains the leading cause of death among people living with HIV (PLHIV). At CDC, we are committed to supporting increased access to TB preventive treatment (TPT) – a proven, lifesaving intervention for PLHIV – a population that is up to 30x more likely to develop active TB than those who do not have HIV.

Placing People at the Center of our Work
Placing People at the Center of our Work

What’s New

Learn how CDC and partners are advancing efforts to end TB through research and innovation.


CDC’s Division of Global HIV & TB offers the following resources, which can be shared across various networks.