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The Advanced Molecular Detection (AMD) program is helping build and integrate laboratory, bioinformatics, and epidemiology technologies across CDC and nationwide. Since 2014, AMD has received support from Congress through—now a $40 million per year appropriation—to implement these technologies in public health programs. With $1.7 billion in multi-year funding from the American Rescue Plan Act of 2021, the AMD program is supporting state, local, and territorial public health laboratories with more staff and resources to collect specimens for COVID-19 testing, sequence them to identify and track SARS-CoV-2 variants, and share data.

In addition to the current investments in state and local jurisdictions included in the data below, CDC has been supporting national SARS-CoV-2 sequencing capacity through contracts with diagnostic laboratories, which have been awarded over $451 million to sequence specimens from across the United States. This enhanced capacity is helping to provide consistent national baseline monitoring for SARS-CoV-2 variant surveillance and risk assessment.

As part of its multi-year plan to strengthen genomic sequencing across the US, CDC will continue to support innovative research and the application of modern genomic epidemiology in the public health system, including the creation of Centers of Excellence to help develop new tools and techniques. Efforts also will focus on building and supporting a national bioinformatics infrastructure that will create a unified system for sharing and analyzing sequence data.

NOTE: Map content and related pages reflect cumulative investments in FY2021- FY2023. They will be updated as support is distributed through the ELC and other funding mechanisms.

AMD Regional Workforce Development Training Leads provide support to labs within the region and across regions on cross-cutting AMD training to help staff develop the critical skills necessary to extract, analyze, and interpret sequencing data. Regional training may incorporate local or regional resources or collaboration with academic institutions.

AMD Regional Bioinformatics Support Leads act as regional consultants. Often referred to as Bioinformatics Regional Resource, or BRRs, they provide support to labs within the region and across regions to help develop national bioinformatics. The state public health lab serving as the BRR may also be the AMD Training Lead for the region. In addition to assisting with training, BRRs assist state and local staff with data analysis. They also consult with local or state IT departments, CDC, and other partners on how to implement or expand the use of AMD technologies.

The PGCoE network is intended to foster and improve innovation and technical capacity in pathogen genomics, molecular epidemiology, and bioinformatics to better prevent, control. and respond to microbial threats of public health importance. Combined, the PGCOEs will serve as a network to: perform a landscape analysis of gaps, needs and opportunities for genomics in the United States public health system; pilot and implement genomics technologies and applications for public health; and prepare for and respond to infectious disease threats.

  • The Georgia Department of Public Health will partner with six academic institutions: University of Georgia, Georgia Tech Research Institute, Emory University, Augusta University, Georgia State University, and the University of Texas Health Science Center at Houston.
  • The Massachusetts Department of Public Health will partner with the Broad Institute of MIT and Harvard as lead academic partner. Other partners from Massachusetts and Connecticut include Boston University, Mass General Brigham hospital network, Yale University, Fathom Information Design, and Theiagen Genomics . In addition, it will serve as lead CoE for education with Harvard Medical School, the Broad Institute of MIT and Harvard, and the Massachusetts Consortium on Pathogen Readiness (MassCPR).
  • The Minnesota Department of Health will have the University of Minnesota and the Mayo Clinic as primary partners.
  • The Virginia Division of Consolidated Laboratory Services will partner with the Virginia Department of Health, Virginia Commonwealth University, and the University of Virginia.
  • The Washington State Department of Health will partner with the University of Washington, Fred Hutchinson Cancer Center, and the Washington Animal Disease Diagnostic Laboratory as well as with Public Health – Seattle & King County.