Advanced Molecular Detection (AMD) and Response to Infectious Disease Outbreaks

Advanced molecular detection (AMD) integrates the latest next-generation genomic sequencing technologies with bioinformatics and epidemiology expertise across CDC and the nation to help us find, track, and stop disease-causing pathogens faster than ever before.

NGS Quality Initiative releases new tools

Posted on Friday, July 31, 2020

The CDC and APHL Next Generation Sequencing (NGS) Quality Initiative released the next set of ready-to-implement tools and documents. Adding to the collection of documents for Illumina Miseq, Oxford Nanopore’s MinION, and ThermoFisher’s Ion Torrent, this set of products includes SOPs for training personnel on Illumina’s MiniSeq and NextSeq. Additionally, this set provides tools and documents for two new Quality System Essentials (QSEs):  Information Management and Assessment. Within this release are documents on best practices for documenting bioinformatic pipelines to support reproducibility under the Information Management QSE. This release also contains documents on identifying, developing, and applying key performance indicators to your sequencing assays and a Quality Management System Internal Assessment Tool to help laboratories assess compliance with quality system recommendations under the Assessment QSE.

Page last reviewed: July 31, 2020