Recommendations for Fully Vaccinated People
COVID-19 Homepage
COVID-19 Vaccines for People Who Are Moderately or Severely Immunocompromised
COVID-19 vaccine recommendations have been updated as of April 19. Learn more.
- If you are moderately or severely immunocompromised (have a weakened immune system), you are at increased risk of severe COVID-19 illness and death. Additionally, your immune response to COVID-19 vaccination may not be as strong as in people who are not immunocompromised.
- As with vaccines for other diseases, you are protected best when you stay up to date with your COVID-19 vaccines for your age group:
- COVID-19 vaccine and booster recommendations may be updated as CDC continues to monitor the latest COVID-19 data.
Updated Pfizer-BioNTech vaccine:
- Children aged 6 months–4 years who completed their primary series with 3 doses of the original Pfizer-BioNTech COVID-19 vaccine are recommended to receive an updated Pfizer-BioNTech booster.
- Children aged 6 months-4 years who completed their primary series with 2 doses of the original Pfizer-BioNTech vaccine and a 3rd dose of the updated Pfizer-BioNTech vaccine are not currently recommended to get an updated Pfizer-BioNTech booster.
To find COVID-19 vaccine locations near you: Search vaccines.gov, text your ZIP code to 438829, or call 1-800-232-0233.
Who Is Moderately or Severely Immunocompromised?
Some people are immunocompromised (have a weakened immune system) due to a medical condition or from receipt of immunosuppressive medications or treatments. Learn more about which medical conditions put you at increased risk of severe COVID-19 illness and death. You can self-attest to your moderately or severely immunocompromised status, which means you do not need any documentation of your status to receive COVID-19 vaccine doses you might be eligible to receive.
People Who Were Vaccinated Outside of the United States
People who are moderately or severely immunocompromised and who received COVID-19 vaccines not available in the United States should either complete or restart the recommended COVID-19 vaccine series, including a booster, in the United States. For more information, talk to your healthcare provider, or see the COVID-19 Interim Clinical Considerations.