Reported Tuberculosis in the United States, 2021

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Executive Commentary

Executive Commentary

Tables

Table 1. Tuberculosis Cases, Incidence Rates per 100,000 Population, Deaths, Death Rates per 100,000 Population, and Percent Change: United States, 1953–2021
Table 2. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population by Hispanic Ethnicity and Non-Hispanic Race:¹ United States, 1993–2021
Table 3. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population Among U.S.-Born Persons¹by Hispanic Ethnicity and Non-Hispanic Race:² United States, 1993–2021
Table 4. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population Among Non-U.S.–Born Persons¹by Hispanic Ethnicity and Non-Hispanic Race: United States, 1993–2021
Table 5. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population by Age Group: United States, 1993–2021
Table 6. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population Among U.S.-Born Persons¹ by Age Group: United States, 1993–2021
Table 7. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population Among Non-U.S.–Born Persons¹ by Age Group: United States, 1993–2021
Table 8. Tuberculosis Cases and Percentages¹ by Birth Decade Cohort Among U.S.-Born Persons:² United States, 1993–2021
Table 9. Tuberculosis Cases and Percentages¹ by Birth Decade Cohort Among Non-U.S.–Born Persons:² United States, 1993–2021
Table 10. Tuberculosis Cases, Percentages, and Incidence Rates per 100,000 Population by Origin of Birth:¹ United States, 1993–2021
Table 11. Tuberculosis Cases and Percentages Among Non-U.S.–Born Persons¹ by the Top 30 Countries² of Birth: United States, 2017–2021
Table 12. 5-Year Tuberculosis Incidence Rates per 100,000 Population in the United States by Country of Birth¹, 2017–2021
Table 13. Tuberculosis Percentages Among Non-U.S.–Born Persons¹ by Number of Years in the United States Prior to TB Diagnosis, 1993–2021
Table 14. Tuberculosis Cases and Percentages by Case Verification Criterion and Site of Disease: United States, 1993–2021
Table 15. Tuberculosis Cases and Percentages by Drug Resistance and History of Previous TB: United States, 1993–2021
Table 16. Tuberculosis Cases and Percentages Among U.S.-Born Persons¹ by Drug Resistance and History of Previous TB Disease: United States, 1993–2021
Table 17. Tuberculosis Cases and Percentages Among Non-U.S.–Born Persons¹ by Drug Resistance and History of Previous TB Disease: United States, 1993–2021
Table 18. Percentages of Tuberculosis Cases by Initial Drug Regimen, Method of Administration, and Completion of Therapy (COT): United States, 1993–2021
Table 19. Tuberculosis Cases and Percentages Among Persons with HIV¹ Test Results² and with HIV Coinfection by Age Group:³ United States, 2011–2021
Table 20. Tuberculosis Cases and Percentages by Reason Tuberculosis Therapy Was Stopped: United States, 1993–2019¹
Table 21. Deaths Reported Among Persons with Tuberculosis Disease: United States, 2010–2019¹
Table 22. Sputum Culture Conversion: United States, 2010–2019¹
Table 23. Extrapulmonary Tuberculosis Cases and Percentages by Site of Disease: United States, 2010–2021
Table 24. National Tuberculosis Genotyping Surveillance Coverage:¹ United States, 2004–2021
Table 25. National Tuberculosis Genotyping Surveillance Coverage:¹ United States-Affiliated Reporting Areas,² 2004–2021
Table 26. Genotyped Tuberculosis Cases with Mycobacterium bovis¹by Origin of Birth:²United States, 2004–2021
Table 27. Tuberculosis Cases and Incidence Rates per 100,000 Population by Origin of Birth,¹Sex, and Age Group: United States, 2021
Table 28. Tuberculosis Risk Factors by Origin of Birth¹and Hispanic Ethnicity and Non-Hispanic Race:²United States, 2021
Table 29. Tuberculosis Cases and Percentages by Residence in and Type of Correctional Facilitiy, Ages ≥15 Years: United States, 1993–2021
Table 30. Characteristics of Tuberculosis Cases in GENType Clusters¹ by Alert Levels Based on Log-Likelihood Ratio (LLR):² United States, 2019–2021
Table 31. Tuberculosis Cases and Clusters by Cluster Size:¹ United States, 2019–2021
Table 32. Twenty-Five Most Frequently Reported GENTypes¹ Among Genotyped Tuberculosis Cases: United States,²2019–2021
Table 33. Five Most Frequently Reported GENTypes¹ Among Genotyped Tuberculosis Cases: United States-Affiliated Reporting Areas,² 2019–2021
Table 34. Tuberculosis Cases and Incidence Rates per 100,000 Population: Reporting Areas, 2021 and 2020
Table 35. Tuberculosis Cases and Percentages by Age Group: Reporting Areas, 2021
Table 36. Tuberculosis Cases by Hispanic Ethnicity and Non-Hispanic Race:¹ Reporting Areas, 2021
Table 37. Tuberculosis Cases and Percentages by Origin of Birth:¹ Reporting Areas, 2021
Table 38. Tuberculosis Cases and Percentages by Pulmonary and Extrapulmonary Disease: Reporting Areas, 2021
Table 39. Tuberculosis Risk Factors: Reporting Areas, 2021
Table 40. Primary Reason for Tuberculosis Evaluation:¹Reporting Areas, 2021
Table 41. Tuberculosis Cases and Percentages by Residence in and Type of Correctional Facilities, Ages ≥15 Years: Reporting Areas, 2021
Table 42. Tuberculosis Cases and Percentages¹ by Social Risk Factors, Ages ≥15 Years: Reporting Areas, 2021
Table 43. Tuberculosis Cases and Percentages by Primary Occupation,¹ Ages ≥15 Years: Reporting Areas, 2021
Table 44. Tuberculosis Cases and Percentage by Initial Drug Regimen: Reporting Areas, 2021
Table 45. Culture-Positive Tuberculosis Cases and Percentages with Drug-Susceptibility Testing (DST) Results by Resistance to Isoniazid or Multidrug Resistance (MDR): Reporting Areas, 2021
Table 46. Tuberculosis Cases and Percentages by HIV Status:¹ Reporting Areas, 2021
Table 47. Tuberculosis Genotyping Surveillance Coverage:¹ Reporting Areas, 2021
Table 48. Tuberculosis Cases and Percentages by Method of Administration: Reporting Areas, 2019¹
Table 49. Tuberculosis Cases and Percentages by Completion of Tuberculosis Therapy (COT):¹Reporting Areas, 2019²
Table 50. Number and Percentages¹of Persons with TB Disease who Completed Therapy Within ¹ Year: Reporting Areas, 2015-2019²
Table 51. Tuberculosis Cases and Incidence Rates per 100,000 Population: Metropolitan Statistical Areas with ≥500,000 Population, 2021 and 2020
Table 52. Tuberculosis Cases and Percentages Estimated to be Attributed to Recent Transmission and Extensive Recent Transmission: Reporting Areas, 2020–2021
Table 53. Tuberculosis Cases and Percentages Estimated to be Attributed to Recent Transmission and Extensive Recent Transmission: Counties with >5 Percent Estimated Extensive Recent Transmission, 2020–2021
Table 54. Characteristics of Tuberculosis Cases Estimated to be Attributed to Recent Transmission and Extensive Recent Transmission: United States, 2020–2021

Figures

Figure 1. Estimated Cases Attributed to Recent Transmission of Tuberculosis, United States, 2020–2021
Figure 2. Estimated Percentage of Extensive Recent Transmission of Tuberculosis in Counties with 10 or More Genotyped Cases, United States, 2020–2021

Technical Notes

Technical Notes

Tuberculosis in the United States Slide Set

Tuberculosis in the United States Slide Set
Download complete set – (68 slides) [PPT – 8 MB]
PDF Version [PDF – 2 MB]
Slide Set Narrative [PDF – 344 KB]
Archived Surveillance Slide Sets

Appendices

Acknowledgements
Appendix A: Tuberculosis Case Definition for Public Health Surveillance
Appendix B: Recommendations for Reporting and Counting Tuberculosis Cases
Appendix C: Genotyping Background Information & Glossary

Reported Tuberculosis in the United States, 2021

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