Reported Tuberculosis in the United States, 2021

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Table 14. Tuberculosis Cases and Percentages by Case Verification Criterion and Site of Disease: United States, 1993–2021

See Surveillance Slide #39, #40, and #41.

Tuberculosis cases and percentages by case verficiation criterion and site of disease.
Year Total cases Verification criterion1 Site of disease
Positive culture Positive NAA2 Positive smear Clinical case definition Provider diagnosis Pulmonary3 Extrapulmonary4
No. (%) No. (%) No. (%) No. (%) No. (%) No. (%) No. (%)
2021 7,882 6,244 (79.2) 234 (3.0) 24 (0.3) 1,035 (13.1) 345 (4.4) 6,205 (78.8) 1,667 (21.2)
2020 7,171 5,697 (79.4) 193 (2.7) 23 (0.3) 960 (13.4) 298 (4.2) 5,660 (79.0) 1,509 (21.0)
2019 8,898 7,101 (79.8) 187 (2.1) 32 (0.4) 1,217 (13.7) 361 (4.1) 7,080 (79.6) 1,813 (20.4)
2018 8,998 7,096 (78.9) 234 (2.6) 34 (0.4) 1,269 (14.1) 365 (4.1) 7,193 (80.0) 1,802 (20.0)
2017 9,069 7,129 (78.6) 191 (2.1) 31 (0.3) 1,335 (14.7) 383 (4.2) 7,181 (79.2) 1,882 (20.8)
2016 9,240 7,171 (77.6) 182 (2.0) 37 (0.4) 1,410 (15.3) 440 (4.8) 7,364 (79.8) 1,868 (20.2)
2015 9,538 7,413 (77.7) 173 (1.8) 44 (0.5) 1,466 (15.4) 442 (4.6) 7,630 (80.0) 1,904 (20.0)
2014 9,382 7,217 (76.9) 161 (1.7) 45 (0.5) 1,494 (15.9) 465 (5.0) 7,457 (79.5) 1,921 (20.5)
2013 9,539 7,356 (77.1) 148 (1.6) 47 (0.5) 1,501 (15.7) 487 (5.1) 7,571 (79.4) 1,967 (20.6)
2012 9,923 7,616 (76.8) 118 (1.2) 38 (0.4) 1,641 (16.5) 510 (5.1) 7,839 (79.0) 2,078 (21.0)
2011 10,474 8,059 (76.9) 121 (1.2) 61 (0.6) 1,671 (16.0) 562 (5.4) 8,310 (79.4) 2,161 (20.6)
2010 11,071 8,390 (75.8) 107 (1.0) 69 (0.6) 1,860 (16.8) 645 (5.8) 8,661 (78.2) 2,409 (21.8)
2009 11,494 8,863 (77.1) 57 (0.5) 73 (0.6) 1,775 (15.4) 726 (6.3) 8,994 (78.3) 2,488 (21.7)
2008 12,943 10,083 (77.9) 18 (0.1) 60 (0.5) 1,538 (11.9) 1,244 (9.6) 10,285 (79.5) 2,654 (20.5)
2007 13,274 10,439 (78.6) –– –– 69 (0.5) 1,477 (11.1) 1,289 (9.7) 10,589 (79.8) 2,680 (20.2)
2006 13,720 10,747 (78.3) –– –– 92 (0.7) 1,620 (11.8) 1,261 (9.2) 10,850 (79.1) 2,865 (20.9)
2005 14,053 10,955 (78.0) –– –– 94 (0.7) 1,789 (12.7) 1,213 (8.6) 11,124 (79.2) 2,923 (20.8)
2004 14,498 11,330 (78.1) –– –– 79 (0.5) 1,821 (12.6) 1,268 (8.7) 11,525 (79.5) 2,969 (20.5)
2003 14,832 11,687 (78.8) –– –– 115 (0.8) 1,777 (12.0) 1,253 (8.4) 11,808 (79.7) 3,014 (20.3)
2002 15,054 11,979 (79.6) –– –– 104 (0.7) 1,815 (12.1) 1,156 (7.7) 11,907 (79.1) 3,141 (20.9)
2001 15,943 12,756 (80.0) –– –– 122 (0.8) 1,879 (11.8) 1,186 (7.4) 12,726 (79.8) 3,213 (20.2)
2000 16,306 13,014 (79.8) –– –– 148 (0.9) 1,947 (11.9) 1,197 (7.3) 13,085 (80.3) 3,209 (19.7)
1999 17,493 13,995 (80.0) –– –– 170 (1.0) 2,098 (12.0) 1,230 (7.0) 14,063 (80.4) 3,426 (19.6)
1998 18,288 14,792 (80.9) –– –– 155 (0.8) 2,252 (12.3) 1,089 (6.0) 14,804 (81.0) 3,482 (19.0)
1997 19,753 15,981 (80.9) –– –– 155 (0.8) 2,411 (12.2) 1,206 (6.1) 16,241 (82.2) 3,509 (17.8)
1996 21,212 17,156 (80.9) –– –– 131 (0.6) 2,607 (12.3) 1,318 (6.2) 17,387 (82.0) 3,814 (18.0)
1995 22,727 18,266 (80.4) –– –– 189 (0.8) 2,749 (12.1) 1,523 (6.7) 18,887 (83.1) 3,834 (16.9)
1994 24,207 19,508 (80.6) –– –– 189 (0.8) 2,917 (12.1) 1,593 (6.6) 20,317 (83.9) 3,886 (16.1)
1993 25,105 20,309 (80.9) –– –– 185 (0.7) 3,088 (12.3) 1,523 (6.1) 21,156 (84.3) 3,940 (15.7)

1Based on the public health surveillance case definition for tuberculosis; see Appendix A.
2Nucleic Acid Amplification test. Information not collected before 2008.
3Persons with pulmonary as the only site of disease and persons with both pulmonary and extrapulmonary sites of disease.
4Persons with extrapulmonary TB disease only.

Note: Data for all years are updated through July 8, 2022.

Double dashes (––) indicate that data are not available.

See Technical Notes