Malaria Information and Prophylaxis, by Country [C]
| Country | Areas with Malaria | Drug Resistance2 | Malaria Species3 | Recommended Chemoprophylaxis4 | Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries |
|---|---|---|---|---|---|
| Cambodia | Present throughout the country. None or negligible transmission in the cities of Phnom Penh and Siem Reap, and at the main temple complex at Angkor Wat. | Chloroquine
Mefloquine |
P. vivax 80%; P. falciparum 20%; P. knowlesi 7 rare | Atovaquone-proguanil, doxycycline, or tafenoquine5. |
1) City(ies) of travel |
| Cameroon | All | Chloroquine | Primarily P. falciparum. Less commonly, P. malariae, P. ovale, or P. vivax | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Canada | None | Not Applicable | Not Applicable | Not Applicable | |
| Canary Islands (Spain) | None | Not Applicable | Not Applicable | Not Applicable | |
| Cape Verde | No indigenous cases reported since 2018. Previously, rare cases on Santiago (São Tiago) Island and Boa Vista Island. | Previously, chloroquine | Previously, primarily P. falciparum | None (mosquito avoidance only)6 | Island of Travel Map of Cape Verde |
| Cayman Islands (U.K.) | None | Not Applicable | Not Applicable | Not Applicable | |
| Central African Republic | All | Chloroquine | Primarily P. falciparum. Less commonly, P. malariae, P. ovale, or P. vivax | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Chad | All | Chloroquine | Primarily P. falciparum. Less commonly, P. malariae, P. ovale, or P. vivax | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Chile | None | Not Applicable | Not Applicable | Not Applicable | |
| China | None | Not Applicable | Not Applicable | Not Applicable | |
| Christmas Island (Australia) | None | Not Applicable | Not Applicable | Not Applicable | |
| Cocos (Keeling) Islands (Australia) | None | Not Applicable | Not Applicable | Not Applicable | |
| Colombia | All areas <1,700 m (5,577 ft). None in Bogotá, Cartagena, and Medellin. | Chloroquine | P. falciparum 50%,
P. vivax 50% |
Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | 1) City(ies) of travel
2) Altitude of city(ies) of travel Altitude information for Colombia |
| Comoros | All | Chloroquine | Primarily P. falciparum. P. malariae and P. vivax rare | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Congo, Republic of the (Congo-Brazzaville) | All | Chloroquine | Primarily P. falciparum. Less commonly, P. malariae, P. ovale, or P. vivax | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Cook Islands (New Zealand) | None | Not Applicable | Not Applicable | Not Applicable | |
| Costa Rica | Present in the provinces of Alajuela and Limón.
Rare to no transmission in other parts of the country. |
None | P. falciparum 86%, P. vivax 14% | Alajuela and Limón Provinces: Atovaquone-proguanil, chloroquine, doxycycline, mefloquine, or tafenoquine. All other areas: None (mosquito avoidance only.)6 | Malaria Outbreak Reported in Costa Rica. (4/17/2023) |
| Côte d’Ivoire | All | Chloroquine | Primarily P. falciparum. Less commonly, P. malariae, P. ovale, or P. vivax | Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine5 | |
| Croatia | None | Not Applicable | Not Applicable | Not Applicable | |
| Cuba | None | Not Applicable | Not Applicable | Not Applicable | |
| Cyprus | None | Not Applicable | Not Applicable | Not Applicable | |
| Czech Republic | None | Not Applicable | Not Applicable | Not Applicable |
1. Factors that affect local malaria transmission patterns can change rapidly and from year to year, such as local weather conditions, mosquito vector density, and prevalence of infection. Information in these tables is updated regularly.
2. Refers to P. falciparum malaria unless otherwise noted.
3. Estimates of malaria species are based on best available data from multiple sources. Where proportions are not available, the primary species and less common species are identified.
4. Several medications are available for chemoprophylaxis. When deciding which drug to use, consider specific itinerary, length of trip, cost of drug, previous adverse reactions to antimalarials, drug allergies, and current medical history. All travelers should seek medical attention in the event of fever during or after return from travel to areas with malaria.
5. Primaquine and tafenoquine can cause hemolytic anemia in persons with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Before prescribing primaquine or tafenoquine, patients must be screened for G6PD deficiency using a quantitative test.
6. Mosquito avoidance includes applying topical mosquito repellant, sleeping under an insecticide treated bed net, and wearing protective clothing (e.g., long pants and socks, long sleeve shirt). For additional details on mosquito avoidance, see: https://www.cdc.gov/malaria/travelers/index.html
7. P. knowlesi is a malaria species with a simian host (macaque). Human cases have been reported from most countries in Southeast Asia and are associated with activities in forest or forest-fringe areas. This species of malaria has no known resistance to antimalarials.