Antimalarial Drug Resistance Testing

For Health Care Providers

At a glance

  • CDC strives to track antimalarial drug resistance among imported malaria cases diagnosed in the United States. Doing so requires receipt of a patient specimen for laboratory analysis.
  • Send specimens from all malaria cases diagnosed in the U.S. to CDC's Malaria Laboratory for drug-resistance testing.
A HCP holds a blood tube collection in a rack.

Test for Drug Resistance

CDC conducts surveillance for molecular markers of antimalarial resistance. Whole blood specimens from all malaria cases diagnosed in the U.S. should be sent to the CDC Malaria Laboratory for this testing. Please contact malarialab@cdc.gov for information on specimen submission.

Molecular characterization: For some drugs (chloroquine, sulfadoxine-pyrimethamine and similar drugs, atovaquone, artemisinins), molecular markers have been identified that confer resistance. Molecular techniques, such as PCR or gene sequencing can identify these markers in blood taken from malaria-infected patients.

Content Source
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
About This Page
Published: May 15, 2024
Updated: July 15, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: July 15, 2024

The information on this page was last reviewed by subject matter experts to ensure accuracy.