Influenza Vaccine Composition for the 2016–17 Season

All influenza vaccines licensed in the United States will contain HA derived from influenza viruses antigenically identical to those recommended by FDA (451). Both trivalent and quadrivalent influenza vaccines will be available in the United States (Table 1). The 2016–17 U.S. influenza vaccines will contain HA derived from the following:

  • an A/California/7/2009 (H1N1)–like virus,
  • an A/Hong Kong/ 4801/2014 (H3N2)–like virus, and
  • a B/Brisbane/60/2008–like virus (Victoria lineage).

The 2016–17 U.S. quadrivalent vaccines will contain the same three antigens, and an additional influenza B virus HA, derived from a B/Phuket/3073/2013–like virus (Yamagata lineage). The composition for 2016–17 represents a change in the influenza A(H3N2) virus and a switch in lineage for the influenza B viruses.