How CDC Classifies Flu Severity
In 2017, CDC adopted and outlined a new methodology for classifying flu season severity. Based on data from past flu seasons, CDC researchers used key flu indicator data to develop intensity thresholds (ITs) to classify the severity of flu seasons. This methodology was published in the American Journal of Epidemiology in October 2017.
Based on the intensity thresholds, CDC researchers have classified seasonal severity from 2003-2004 through the 2018-2019 flu seasons. Overall, four seasons were classified as low severity, 9 as moderate, three as high, and none as very high.
In addition to assessing the severity of annual flu seasons, this methodology can also be used to determine severity during a flu pandemic.
How does CDC track flu activity?
CDC tracks flu activity through key flu indicators, including the percentage of influenza-like illness (ILI) visits to outpatient health clinics, the rates of influenza-associated hospitalizations, and the percentage of deaths resulting from pneumonia or flu.
How does CDC define “severity”?
CDC began using a new approach published in 2017 to define flu season severity. CDC first calculates intensity thresholds [ITs] for three key flu indicators using data from past flu seasons. CDC then classifies the severity of specific flu seasons by determining whether the indicator values during the peak of each flu season crossed their respective ITs.
What did researchers do to classify the severity of flu seasons in this study?
Flu severity was assessed using the following data :
- the percentage of visits to outpatient clinics for ILI,
- the rates of influenza-associated hospitalizations, and
- the percentage of deaths resulting from pneumonia or influenza that occurred during each season.
The Moving Epidemic Method was then used to translate the data into standardized intensity thresholds (ITs) for each indicator. The peak value of an indicator was compared to the respective IT for that indicator to arrive at a severity classification.
- Severity is classified as “low” if the peak for at least 2 of 3 indicators for the overall population fall below the respective systems’ lowest ITs.
- Severity is classified as “moderate” if the peak for at least 2 indicators for the overall population fall between the respective systems’ lowest and mid-range ITs.
- Severity is classified as “high” if the peak for at least 2 indicators for the overall population fall between the respective systems’ mid-range and high ITs.
- Severity is classified as “very high” if the peak for at least 2 indicators for the overall population fall above the respective systems’ highest ITs.
- Severity was also assessed by age group.
What are intensity thresholds and why are they important?
An intensity threshold is a value developed using data from past flu seasons that help assess the chance that an influenza indicator, like influenza-like-illness (ILI) or influenza percent positive, will go above a certain threshold. In this instance, intensity thresholds (ITs) are important because they help researchers classify flu severity based on the level of flu activity at the peak of the season. For this study, ITs were developed for the overall population and further separated into three age groups: children, adults, and older adults. The ITs used in the paper correspond to a 50% (1 in 2), 10% (1 in 10) and 2% (1 in 50) chance of exceedance during an influenza season. These threshold values were used to classify flu severity into low, moderate, high, and very high categories and then applied to U.S. seasons from 2003–04 through the 2015–16, including the 2009 pandemic.
Has the method used to define “severity” changed?
Before this methodology was adopted in 2017, CDC used various criteria to subjectively determine severity, including visits to outpatient clinics, the number of flu-positive respiratory specimens, hospitalizations, and deaths. By contrast, intensity thresholds give researchers the ability to determine flu season severity systematically.
Why is it important to assess flu season severity?
By measuring the severity of influenza seasons, CDC can use key flu indicator data to guide public health actions, such as targeting prevention and treatment messages to appropriate audiences and make recommendations designed to prevent flu illnesses and death. See systematic assessment.