Effectiveness Research

Effectiveness research assesses whether interventions and strategies to prevent, diagnose, treat, and monitor diabetes work. This research is designed to inform patients, providers, and decision makers which interventions or strategies are most effective for which populations or populations of patients, and under what circumstances.

The ball is in your court
Current Research Projects
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  • Diabetes Prevention Program Outcome Study (DPPOS)
    The DPPOS study assesses the long-term effects of the intensive lifestyle intervention or metformin on diabetes-related complications and cancer. This a follow-up study of a multicenter, randomized control trial called the Diabetes Prevention Program (DPP). The DPP showed that people who are at high risk for type 2 diabetes can prevent or delay the disease by losing a modest amount of weight through lifestyle changes (dietary changes and increased physical activity) and is also cost effective, providing the evidence base for CDC’s National DPP.
  • The Action for Health in Diabetes (Look AHEAD)-Extension
    The Look AHEAD-Extension study assesses the long-term effect of the intensive lifestyle intervention on life expectancy, health care costs, and the key dimensions of healthy aging (less frailty, reduced diabetic small blood vessel complications, and improved quality of life).
  • 30-Year Follow-up of Da Qing Diabetes Prevention Study
    The 30-year follow-up of the Da Qing Diabetes Prevention Study (DQDPS) examines the long-term effects of lifestyle changes on major cardiovascular (heart) disease, microvascular (small blood vessel) complications (e.g., eye and kidney diseases), and life expectancy.
Recent Publications