2021 National Viral Hepatitis Progress Report
The Centers for Disease Control and Prevention (CDC) strives to prevent viral hepatitis infections and eliminate disease and mortality caused by viral hepatitis. The National Viral Hepatitis Progress Report provides information on progress in the implementation of recommended interventions and the impact these interventions are having on prevention of viral hepatitis transmission, disease, and associated mortality. In 2020, CDC modified the goals and associated targets from previous reports to align them with CDC’s Division of Viral Hepatitis 2025 Strategic Plan pdf icon[PDF – 3 MB] and HHS’s Viral Hepatitis National Strategic Planexternal icon for 2021-2025.
Report At-A-Glance
Ten indicators provide an objective way to assess progress toward achieving key viral hepatitis goals. Select the indicator from the table below for more information.
| Baseline 2017 data year |
2019 Observed (Annual Target*) |
2025 Goal 2023 data year |
Status | |
|---|---|---|---|---|
| Reduce estimated† new hepatitis A virus infections by ≥40% | 6,700 | 37,700 (5,800) |
4,000 |  |
| Reduce estimated† new hepatitis B virus infections by ≥20% | 22,200 | 20,700 (20,800) |
18,000 |  |
| Reduce reported rate‡ of new hepatitis B virus infections among persons who inject drugs¶ by ≥25% | 1.4 | 1.2 (1.3) |
1.0 | |
| Reduce reported rate‡of hepatitis B-related deaths by ≥20% | 0.46 | 0.42 (0.43) |
0.37 | |
| Reduce reported rate‡ of hepatitis B-related deaths among Asian and Pacific Islander persons by ≥25% | 2.45 | 2.10 (2.25) |
1.84 | |
| Reduce estimated† new hepatitis C virus infections by ≥20% | 44,700 | 57,500 (41,467) |
35,000 | |
| Reduce reported rate‡ of new hepatitis C virus infections among persons who inject drugs¶ by ≥25% | 2.3 | 2.8 (2.1) |
1.7 | |
| Reduce reported rate‡ of hepatitis C-related deaths by ≥20% | 4.13 | 3.33 (3.75) |
3.00 | |
| Reduce reported rate‡ of hepatitis C-related deaths among American Indian and Alaska Native persons by ≥30% | 10.24 | 8.63 (9.22) |
7.17 | |
| Reduce reported rate‡ of hepatitis C-related deaths among non-Hispanic Black persons by ≥30% | 7.03 | 5.44 (6.33) |
4.92 | |
| *Annual targets assume a constant (linear) rate of change from the observed baseline (2017) to the 2025 goal (2023 data year). †The number of estimated viral hepatitis infections was determined by multiplying the number of reported cases by a factor that adjusted for underascertainment and underreporting (CDC 2019 Viral Hepatitis Surveillance Report and Klevens, et al, 2014). ‡Per 100,000 population. ¶Persons aged 18–40 years were used as a proxy for persons who inject drugs. |
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|
Met or exceeded current annual target |  |
Moving toward annual target, but annual target was not fully met | |
Annual target was not met and has not changed or moved away from annual target |
The ten indicators and accompanying 2025 goals compiled specifically for the National Progress Report are consistent with CDC’s Division of Viral Hepatitis 2025 Strategic Plan.
Key Findings
- Large increases in hepatitis A during 2019 were associated with ongoing widespread outbreaks driven by person-to-person transmission. Outbreaks occurred among adults reporting homelessness or who use drugs, and demonstrate the importance of surveillance to identify, and vaccination to prevent and respond to, outbreaks of hepatitis A.
- All four hepatitis B indicators met the annual target for 2019, and incidence of new hepatitis B virus infections met the annual target for the first time in 2019. However, only minimal progress has been made to reduce new infections overall. Continued efforts are needed to increase infant and at-risk adult vaccination rates and improve appropriate testing and linkage to care.
- Increases in injection drug use related to the nation’s drug crisis have contributed to increases in new hepatitis C virus (HCV) infections. Efforts must continue to connect all people experiencing new or chronic infection to well-tolerated, short-course treatments that cure most persons infected with HCV, preventing disease progression and transmission. Syringe services programs and medication for substance use disorder are also key services for preventing HCV transmission; there is no vaccine for hepatitis C.
- As with hepatitis B, the nation continues to make progress towards reducing deaths related to hepatitis C; however, continued efforts are needed to identify new and chronic infections, and ensure all people with hepatitis C, including persons who inject drugs, receive treatment.
Annual Reports of Progress Toward 2025 Goals
2020 National Viral Hepatitis Progress Report – published in 2020 and included data through 2018.
Annual Reports of Progress Toward 2020 Goals
2019 National Viral Hepatitis Progress Report – published in 2019 and included data through 2017.
2018 National Viral Hepatitis Progress Report – published in 2018 and included data through 2016.
Inaugural Report
Progress Toward Viral Hepatitis Elimination in the United States pdf icon[PDF – 46 pages] was the inaugural report published in 2017 that included data through 2015. The comprehensive report highlighted the nation’s progress at the time toward reducing the burden of hepatitis A, hepatitis B, and hepatitis C.