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Longitudinal Spatial Analysis of Health-Related Quality of Life in Mississippi: Clustering, Trends, and Socioeconomic Drivers
ORIGINAL RESEARCH — Volume 23 — September 10, 2026
PEER REVIEWED
| LISA cluster classification | Counties | |
|---|---|---|
| 2016 (n = 22) | 2025 (n = 15) | |
| High-High | Coahoma, Humphreys, Leflore, Sharkey, Sunflower, Tallahatchie, Washington, Yazoo | Carroll, Coahoma, Grenada, Humphreys, Leflore, Quitman, Sunflower, Tallahatchie, Washington |
| Low-Low | Forrest, George, Hancock, Harrison, Hinds, Jackson, Marshall, Pearl River, Perry, Stone | Hinds, Marshall, Rankin, Stone |
| Low-High | Carroll, Franklin, Warren | Attala |
| High-Low | Scott | Scott |
Figure 1. Local indicators of spatial association (LISA) cluster maps for the principal component analysis–based composite health-related quality-of-life score in Mississippi Counties. A) 2016; B) 2025. Data source: County Health Rankings & Roadmaps, 2015–2025 releases.
| EHSA trend classification | No. of counties | County names |
|---|---|---|
| Consecutive cold spot | 4 | Jefferson Davis, Oktibbeha, Panola, Pearl River |
| Consecutive hot spot | 3 | Jefferson, Leflore, Marion |
| New hot spot | 1 | Jackson |
| Sporadic cold spot | 8 | Hinds, Lamar, Lauderdale, Madison, Monroe, Tate, Tunica, Winston |
| Sporadic hot spot | 9 | Benton, Claiborne, Coahoma, Itawamba, Sharkey, Smith, Warren, Wayne, Yazoo |
| No pattern detected | 57 | All others |
Figure 2. Emerging hot spot analysis (EHSA) of trends in health-related quality-of-life scores in Mississippi counties from 2015 through 2025. Data source: County Health Rankings & Roadmaps, 2015–2025 releases.
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