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Table 2.7. Number and rates* of deaths with hepatitis B virus infection listed as a cause of death† among residents, by state or jurisdiction — United States, 2015–2019
Source: CDC, National Center for Health Statistics, Multiple Cause of Death 1999–2019 on CDC WONDER Online Database. Data are from the 2015–2019 Multiple Cause of Death files and are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (e.g., nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Numbers are slightly lower than previously reported for 2015–2016 because of NCHS standards that restrict displayed data to US residents. Accessed at http://wonder.cdc.gov/mcd-icd10.html on January 11, 2021. CDC WONDER data set documentation and technical methods can be accessed at https://wonder.cdc.gov/wonder/help/mcd.html#.
* Rates are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths. Missing data are not included.
† Cause of death is defined as 1 of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev. (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).
§UR Unreliable rate: Rates where death counts were <20 were not displayed because of the instability associated with those rates.
¶ S Suppressed: Subnational data representing <10 deaths (0–9) are suppressed or CDC WONDER did not have the functionality to calculate rates.
* Rates are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths. Missing data are not included.
† Cause of death is defined as 1 of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev. (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).
§UR Unreliable rate: Rates where death counts were <20 were not displayed because of the instability associated with those rates.
¶ S Suppressed: Subnational data representing <10 deaths (0–9) are suppressed or CDC WONDER did not have the functionality to calculate rates.
Hepatitis B is associated with premature death, elevated rates of death from all causes, and elevated rates of death from liver-related causes, including hepatocellular carcinoma. Although death certificate data can help characterize deaths in the United States associated with hepatitis B, underreporting of hepatitis B as the underlying or contributing cause of death is known to occur. During 2019, the reported number of deaths were suppressed in 17 jurisdictions with <10 deaths, and rates were suppressed for another 8 states with <20 deaths.
Among jurisdictions with death rates available, the highest hepatitis B-associated death rate was observed in Hawaii (1.17 cases per 100,000 population), and the lowest was observed in Illinois and Michigan (0.17 cases per 100,000 population). In total, 14 states had hepatitis B-associated death rates higher than the national average. Four states with the highest number of deaths reported (California, Texas, New York, and Florida) accounted for more than 40% of all hepatitis B-associated deaths reported during 2019.
Source: Bixler D, Zhong Y, Ly KN, et al; CHeCS Investigators. Mortality among patients with chronic hepatitis B infection: the chronic hepatitis cohort study (CHeCS). Clin Infect Dis 2019;68:956–63. doi: 10.1093/cid/ciy598. PMID: 30060032
Hepatitis B Figures and Tables
- Figure 2.1. Number of reported acute hepatitis B virus cases and estimated infections — United States, 2012–2019
- Figure 2.2. Rates of reported acute hepatitis B virus infection, by state — United States, 2018–2019
- Figure 2.3. Rates of reported acute hepatitis B virus infection, by state or jurisdiction — United States, 2019
- Figure 2.4. Rates of reported acute hepatitis B virus infection, by age group — United States, 2004–2019
- Figure 2.5. Rates of reported acute hepatitis B virus infection, by sex — United States, 2004–2019
- Figure 2.6. Rates of reported acute hepatitis B virus infections, by race/ethnicity — United States, 2004–2019
- Figure 2.7. Availability of information regarding risk behaviors or exposures associated with reported cases of acute hepatitis B virus infection — United States, 2019
- Figure 2.8. Rates of deaths with hepatitis B virus infection listed as a cause of death among residents, by jurisdiction — United States, 2019
- Table 2.1. Number and rates of reported cases of acute hepatitis B virus infection, by state or jurisdiction — United States, 2015–2019
- Table 2.2. Number and rates of reported cases of acute hepatitis B virus infection, by demographic characteristics — United States 2015–2019
- Table 2.3. Reported risk behaviors or exposures among reported cases of acute hepatitis B virus infection — United States, 2019
- Table 2.4. Number of newly reported cases of perinatal hepatitis B virus infection, by state or jurisdiction — United States, 2019
- Table 2.5. Number and rates of newly reported cases of chronic hepatitis B virus infection, by state or jurisdiction — United States, 2019
- Table 2.6. Number and rates of newly reported cases of chronic hepatitis B virus infection, by demographic characteristics — United States, 2019
- Table 2.7. Number and rates of deaths with hepatitis B virus infection listed as a cause of death among residents, by state or jurisdiction — United States, 2015–2019
- Table 2.8. Number and rates of deaths with hepatitis B virus infections listed as a cause of death among residents, by demographic characteristics — United States, 2015–2019