Numbers and rates* of reported cases of acute hepatitis C virus infection, by demographic characteristics — United States, 2016-2020

Rates* of reported cases† of acute hepatitis C virus infection, by state or jurisdiction — United States, 2019-2020
Table 2.2.
Characteristics 2016 No. 2016 Rate* 2017 No. 2017 Rate* 2018 No. 2018 Rate* 2019 No. 2019 Rate* 2020 No. 2020 Rate*
Total § 2,967 1.0 3,216 1.0 3,621 1.2 4,136 1.3 4,798 1.5
Age  (yrs)
0-19 86 0.1 103 0.1 81 0.1 63 0.1 57 0.1
20-29 1,135 2.7 1,189 2.7 1,310 3.0 1,262 2.9 1,230 2.8
30-39 868 2.2 937 2.3 1,070 2.6 1,347 3.2 1.526 3.5
40-49 452 1.2 441 1.1 494 1.3 664 1.7 820 2.1
50-59 264 0.6 332 0.8 366 0.9 442 1.1 578 1.4
≥60 141 0.2 185 0.3 295 0.4 358 0.5 586 0.8
Sex
Male 1,627 1.1 1,775 1.2 2,012 1.3 2,471 1.6 3,105 2.0
Female 1,310 0.8 1,431 0.9 1,605 1.0 1,653 1.0 1,687 1.0
Race/ethnicity
American Indian/Alaska Native 70 3.1 67 2.9 83 3.6 83 3.6 48 2.1
Asian/Pacific Islander 25 0.1 23 0.1 29 0.1 36 0.2 76 0.4
Black, non-Hispanic 130 0.3 202 0.5 231 0.6 267 0.7 458 1.1
White, non-Hispanic 2,109 1.1 2,227 1.2 2,405 1.3 2,683 1.4 3,060 1.6
Hispanic 191 0.3 234 0.4 280 0.5 350 0.6 415 0.7
Urbanicity ¶
Urban 2,227 0.8 2,397 0.9 2,782 1.0 3,275 1.2 3,957 1.4
Rural 501 1.2 485 1.1 676 1.6 720 1.7 757 1.7
HHS Region: Regional Office **
Region 1: Boston 471 3.8 391 2.8 172 1.2 237 1.7 329 2.4
Region 2: New York 301 1.0 313 1.1 332 1.2 405 1.4 455 1.6
Region 3: Philadelphia 422 1.4 424 1.4 404 1.4 392 1.3 365 1.2
Region 4: Atlanta 706 1.1 826 1.3 1,056 1.7 1,253 2.0 1,957 2.9
Region 5: Chicago 615 1.2 692 1.3 977 1.9 1,053 2.0 902 1.7
Region 6: Dallas 95 0.2 105 0.2 114 0.3 157 0.4 384 0.9
Region 7: Kansas City 41 0.4 70 0.6 89 0.8 74 0.5 60 0.4
Region 8: Denver 152 1.4 162 1.4 225 1.9 222 1.9 138 1.1
Region 9: San Francisco 76 0.2 138 0.3 133 0.3 222 0.5 71 0.2
Region 10: Seattle 88 0.7 95 0.7 119 0.9 121 0.9 137 1.0

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Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population.

† Reported confirmed cases. For the case definition, see Acute Hepatitis C.

§ Numbers reported in each category may not add up to the total number of reported cases in a year due to cases with missing data or, in the case of race/ethnicity, cases categorized as “Other”.

¶ Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities. Large central metro, large fringe metro, medium metro, and small metro counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.

** US Department of Health and Human Services (HHS) Regions were categorized according to the grouping of states and US territories assigned under each of the ten Department of Health and Human Services regional offices. For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.

This table summarizes the epidemiology of acute hepatitis C in the United States. During 2020, rates of acute hepatitis C were highest among persons aged 20–49 years, males, American Indian/Alaska Native persons, and those living in the US Department of Health and Human Services Region 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee).

Using urbanicity categories defined by the National Center for Health Statistics, from 2019 to 2020 the rates of reported cases of acute hepatitis C increased in urban settings, but in 2020 rates remained slightly higher in rural settings compared with urban settings. Among all acute hepatitis C cases reported during 2020, 57% occurred among persons aged 20–39 years, 72% occurred among non-Hispanic White persons, and 84% occurred in urban areas.

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