Numbers and rates* of deaths with hepatitis B virus infections listed as a cause of death† among residents, by demographic characteristics — United States, 2016-2020

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◀ Table 2.7
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Numbers and rates* of deaths with hepatitis B virus infections listed as a cause of death† among residents, by demographic characteristics — United States, 2016-2020
Table 2.8.
Characteristic 2016 No. 2016 Rate*
(95% CI)		 2017 No. 2017 Rate*
(95% CI)		 2018 No. 2018 Rate*
(95% CI)		 2019 No. 2019 Rate*
(95% CI)		 2020 No. 2020 Rate*
(95% CI)
Total 1,690 0.45
(0.43-0.48)		 1,727 0.46
(0.44-0.49)		 1,649 0.43
(0.41-0.45)		 1,662 0.42
(0.40-0.44)		 1,752 0.45
(0.42-0.47)
Age group (years)
0–34 39 0.03
(0.02-0.04)		 29 0.02
(0.01-0.03)		 32 0.02
(0.01-0.03)		 45 0.03
(0.02-0.04)		 36 0.02
(0.02-0.03)
35–44 116 0.29
(0.23-0.34)		 106 0.26
(0.21-0.31)		 122 0.30
(0.24-0.35)		 110 0.26
(0.21-0.31)		 109 0.26
(0.21-0.31)
45–54 324 0.76
(0.67-0.84)		 323 0.76
(0.68-0.85)		 283 0.68
(0.60-0.76)		 255 0.62
(0.55-0.70)		 269 0.67
(0.59-0.75)
55–64 576 1.39
(1.28-1.50)		 548 1.30
(1.20-1.41)		 520 1.23
(1.12-1.34)		 502 1.18
(1.08-1.29)		 483 1.14
(1.04-1.24)
65–74 383 1.34
(1.20-1.47)		 417 1.40
(1.27-1.54)		 422 1.38
(1.25-1.52)		 484 1.54
(1.40-1.67)		 495 1.52
(1.39-1.65)
≥75 252 1.22
(1.07-1.37)		 303 1.43
(1.27-1.59)		 270 1.23
(1.08-1.38)		 266 1.18
(1.04-1.32)		 360 1.56
(1.40-1.72)
Sex
Male 1,231 0.67
(0.64-0.71)		 1,275 0.70
(0.66-0.74)		 1,191 0.65
(0.61-0.69)		 1,248 0.66
(0.62-0.70)		 1,278 0.66
(0.63-0.70)
Female 459 0.22
(0.20-0.24)		 452 0.23
(0.20-0.25)		 458 0.22
(0.20-0.24)		 414 0.21
(0.19-0.24)		 474 0.22
(0.20-0.24)
Race/ethnicity
White, non-Hispanic 767 0.29
(0.27-0.31)		 776 0.28
(0.26-0.30)		 760 0.27
(0.25-0.29)		 761 0.28
(0.26-0.30)		 745 0.27
(0.25-0.29)
Black, non-Hispanic 315 0.73
(0.65-0.81)		 320 0.74
(0.66-0.83)		 304 0.70
(0.62-0.79)		 291 0.64
(0.56-0.71)		 308 0.67
(0.60-0.75)
Hispanic 128 0.30
(0.25-0.36)		 109 0.26
(0.21-0.32)		 122 0.28
(0.23-0.33)		 117 0.27
(0.21-0.32)		 132 0.28
(0.23-0.33)
Asian/Pacific Islander 454 2.38
(2.16-2.60)		 492 2.45
(2.23-2.67)		 439 2.10
(1.90-2.30)		 463 2.10
(1.90-2.29)		 541 2.46
(2.25-2.67)
American Indian/Alaska Native 16 UR§ 17 UR§ 6 UR§ 20 0.76
(0.46-1.18)		 17 UR§
HHS Region: Regional Office ¶
Region 1: Boston 56 0.28
(0.21-0.37)		 60 0.35
(0.27-0.46)		 64 0.34
(0.26-0.45)		 43 0.22
(0.16-0.30)		 49 0.24
(0.18-0.33)
Region 2: New York 177 0.51
(0.43-0.59)		 166 0.47
(0.39-0.54)		 156 0.44
(0.36-0.51)		 147 0.42
(0.35-0.49)		 154 0.43
(0.36-0.50)
Region 3: Philadelphia 118 0.32
(0.26-0.38)		 128 0.32
(0.27-0.38)		 130 0.35
(0.29-0.41)		 126 0.32
(0.26-0.38)		 135 0.35
(0.29-0.41)
Region 4: Atlanta 345 0.44
(0.39-0.49)		 365 0.45
(0.41-0.50)		 346 0.45
(0.40-0.50)		 348 0.42
(0.38-0.47)		 352 0.43
(0.39-0.48)
Region 5: Chicago 181 0.29
(0.25-0.33)		 184 0.29
(0.24-0.33)		 174 0.28
(0.24-0.33)		 173 0.27
(0.23-0.31)		 212 0.33
(0.29-0.38)
Region 6: Dallas 230 0.51
(0.44-0.57)		 247 0.55
(0.48-0.62)		 230 0.47
(0.41-0.53)		 230 0.48
(0.42-0.55)		 229 0.47
(0.40-0.53)
Region 7: Kansas City 52 0.33
(0.24-0.44)		 50 0.29
(0.22-0.39)		 65 0.38
(0.29-0.48)		 51 0.30
(0.22-0.40)		 51 0.32
(0.23-0.42)
Region 8: Denver 35 0.27
(0.19-0.38)		 48 0.37
(0.27-0.49)		 34 0.25
(0.17-0.35)		 47 0.32
(0.23-0.43)		 54 0.41
(0.31-0.54)
Region 9: San Francisco 415 0.73
(0.66-0.80)		 393 0.69
(0.62-0.76)		 369 0.62
(0.56-0.69)		 394 0.64
(0.57-0.70)		 411 0.66
(0.59-0.72)
Region 10: Seattle 81 0.51
(0.40-0.63)		 86 0.52
(0.41-0.64)		 81 0.47
(0.37-0.59)		 103 0.58
(0.47-0.70)		 105 0.60
(0.48-0.72)
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Source: CDC, National Center for Health Statistics, Multiple Cause of Death 1999–2020 on CDC WONDER Online Database. Data are from the 2016–2020 Multiple Cause of Death files and are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (e.g., nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Numbers are slightly lower than previously reported for 2016 because of NCHS standards that restrict displayed data to US residents. Accessed at CDC WONDER on January 13, 2022. CDC WONDER data set documentation and technical methods can be accessed here.

* Rates for race/ethnicity, sex, HHS region, and the overall total are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths. Missing data are not included.

† Cause of death is defined as one of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).

UR§ Unreliable rate: Rates where death counts were <20 were not displayed because of the instability associated with those rates.

US Department of Health and Human Services (HHS) regions were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional office. For the purposes of this report, regions with US territories (Regions 2 and 9) contain data from states only.

This table summarizes the characteristics of hepatitis B-associated deaths among residents in the United States. During 2020, a total of 1,752 hepatitis B-associated deaths among US residents were reported in the US Multiple Cause of Death data from the National Center for Health Statistics, which corresponds to an age-adjusted death rate of 0.45 cases per 100,000 population.

The US age-adjusted death rates for hepatitis B have been relatively consistent during 2016–2020. In 2020, the mortality rate was highest among Asian/Pacific Islander persons (2.46 deaths per 100,000 population), approximately 9 times the rate among non-Hispanic White persons (0.27 deaths per 100,000 population).

Hepatitis B-associated mortality rates were also higher than the national rate among persons aged 45 years or older, males, and in Health and Human Services Regions 9 (Arizona, California, Hawaii, and Nevada) and 10 (Alaska, Idaho, Oregon, and Washington).

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