Numbers and rates* of deaths with hepatitis A virus infection listed as a cause of death among residents, by demographic characteristics — United States, 2016-2020

Numbers and rates* of deaths with hepatitis A virus infection listed as a cause of death† among residents, by demographic characteristics — United States, 2016-2020
Table 2.2.
Characteristics 2016 No. 2016 Rate* (95% CI) 2017 No. 2017 Rate* (95% CI) 2018 No. 2018 Rate* (95% CI) 2019 No. 2019 Rate* (95% CI) 2020 No. 2020 Rate* (95% CI)
Total 70 0.01
(0.00-0.01)
91 0.02
(0.02-0.03)
171 0.05
(0.04-0.06)
225 0.04
(0.03-0.05)
179 0.04
(0.03 – 0.05)
Age (years)
0-44 6 UR§ 9 UR§ 33 0.02
(0.01-0.02)
24 0.01
(0.01-0.02)
19 UR§
45-64 33 0.04
(0.03-0.06)
35 0.04
(0.03-0.06)
72 0.09
(0.07-0.11)
118 0.14
(0.12-0.17)
72 0.09
(0.07 – 0.11)
≥65 31 0.06
(0.04-0.09)
47 0.09
(0.07-0.12)
66 0.13
(0.10-0.16)
83 0.15
(0.12-0.19)
88 0.16
(0.13 – 0.19)
Sex
Male 38 0.01
(0.01-0.02)
63 0.03
(0.02-0.03)
115 0.07
(0.06-0.08)
159 0.09
(0.07-0.10)
120 0.06
(0.05 – 0.07)
Female 32 0.01
(0.01-0.02)
28 0
(0.00-0.00)
56 0.02
(0.02-0.03)
66 0.04
(0.03-0.05)
59 0.01
(0.01 – 0.02)
Race/ethnicity
White, Non-Hispanic 50 0.02
(0.01-0.02)
69 0.02
(0.02-0.03)
150 0.06
(0.05-0.07)
194 0.09
(0.07-0.10)
147 0.05
(0.04 – 0.06)
Other or not stated 20 22 21 31 32

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Source: CDC, National Center for Health Statistics, Multiple Cause of Death 1999–2020 on CDC WONDER online database. Data are from the 2016–2020 Multiple Cause of Death files and are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (e.g., nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Numbers are slightly lower than previously reported for 2016 because of NCHS standards that restrict displayed data to US residents. * Rates for race/ethnicity, sex, and the overall total are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): less than 1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and greater than or equal to 85. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths. Missing data are not included.

† Cause of death is defined as one of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev. (ICD-10) codes B15 (hepatitis A).

§ UR Unreliable rate: Rates where death counts were less than 20 were not displayed because of the instability associated with those rates.

¶ S Suppressed: CDC WONDER did not have the functionality to calculate rates for the “Other or not stated” race/ethnicity group.

Hepatitis A is a self-limited disease that does not result in chronic infection and rarely results in death. In 2020, a total of 179 deaths with hepatitis A virus infection listed as a cause of death were reported among US residents in the US Multiple Cause of Death data from the National Center for Health Statistics, resulting in an age-adjusted death rate of 0.04 per 100,000 population. The 2020 hepatitis A-associated mortality rate was highest among persons aged 65 years or older (0.16 deaths per 100,000 population).

The mortality rate among males (0.06 deaths per 100,000 population) was 6 times the rate among females (0.01 deaths per 100,000 population). Because of the low number of reported deaths, further stratification by age, racial/ethnicity categories, state, and Department of Health and Human Services region was impossible because of the instability associated with the rates.