The Centers for Disease Control and Prevention (CDC) established an office in Tanzania in 2001 to support HIV/AIDS prevention. The CDC office expanded through the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) program in 2003. The office introduced programs to support the U.S. President’s Malaria Initiative (PMI) in 2006, influenza sentinel surveillance in 2008, and the Global Health Security Agenda in 2015. CDC works with the Government of Tanzania to strengthen tuberculosis prevention efforts for people living with HIV; enhance laboratory, surveillance, and workforce capacity to respond to public health threats and outbreaks like COVID-19; and prevent and control malaria. CDC staff and partners deliver essential programmatic services nationally and across 11 regions of mainland Tanzania and Zanzibar. The CDC Tanzania office adheres to a One CDC model where expertise, programs, and platforms are leveraged to provide the most impactful health outcomes in the country. CDC works closely with the Government of Tanzania and partners to ensure the country is better prepared to prevent, detect, and respond to public health threats to improve the health and well-being of Tanzanians and people worldwide.

During the COVID-19 pandemic, CDC Tanzania worked to maximize public health impact while supporting emergency response and vaccine deployment efforts. The country office team adapted existing activities to sustain health programs and prevent disruptions in health service delivery, identified innovative approaches to enhance and build stronger programs, and leveraged existing technical expertise and programmatic investments to protect the public’s health. This report provides a snapshot of key achievements and activities.