Time-Varying Effects of Parental Alcoholism on Depression
CME ACTIVITY — Volume 14 — December 14, 2017
PEER REVIEWED
Figure 1.
Age-varying effects of parental alcoholism on lifetime major depressive disorder for respondents aged 18–90 years, National Epidemiologic Survey on Alcohol and Related Conditions, Wave III, 2012–2013. Age-varying effects are presented as odds ratios (ORs) across ages; the solid line represents the OR point estimates, and the surrounding shading represents 95% confidence intervals. The horizontal line represents an OR of 1.00.
| Age, y | Parental Alcoholism Lower Limit | Parental Alcoholism Upper Limit | Parental Alcoholism Estimate (Odds Ratio) |
|---|---|---|---|
| 18.0 | 1.195427179 | 2.272260309 | 1.648126734 |
| 18.7272727 | 1.260284189 | 2.275778416 | 1.69355471 |
| 19.4545455 | 1.323772899 | 2.280927531 | 1.737650728 |
| 20.1818182 | 1.385351709 | 2.287849951 | 1.780302458 |
| 20.9090909 | 1.444477368 | 2.296690058 | 1.821405175 |
| 21.6363636 | 1.500622699 | 2.307580984 | 1.860862275 |
| 22.3636364 | 1.553300166 | 2.320625326 | 1.898585711 |
| 23.0909091 | 1.60209056 | 2.335870551 | 1.934496358 |
| 23.8181818 | 1.646673787 | 2.353282051 | 1.968524287 |
| 24.5454545 | 1.686856114 | 2.37271941 | 2.000608968 |
| 25.2727273 | 1.722586815 | 2.393922902 | 2.030699393 |
| 26.0 | 1.753958399 | 2.416515995 | 2.05875412 |
| 26.7272727 | 1.781188888 | 2.440025357 | 2.084741244 |
| 27.4545455 | 1.804590073 | 2.463914416 | 2.108638304 |
| 28.1818182 | 1.824529489 | 2.487622715 | 2.130432116 |
| 28.9090909 | 1.841394202 | 2.510602989 | 2.150118552 |
| 29.6363636 | 1.85556197 | 2.532350392 | 2.167702259 |
| 30.3636364 | 1.867381868 | 2.552421807 | 2.183196327 |
| 31.0909091 | 1.877163724 | 2.570445928 | 2.196621918 |
| 31.8181818 | 1.885174314 | 2.586126186 | 2.208007849 |
| 32.5454545 | 1.891638012 | 2.599238875 | 2.217390145 |
| 33.2727273 | 1.896739946 | 2.609628446 | 2.224811569 |
| 34.0 | 1.900630285 | 2.617201424 | 2.230321118 |
| 34.7272727 | 1.903428782 | 2.621919841 | 2.23397352 |
| 35.4545455 | 1.905229075 | 2.623794732 | 2.235828708 |
| 36.1818182 | 1.906102546 | 2.622879964 | 2.235951291 |
| 36.9090909 | 1.906101639 | 2.619266515 | 2.234410033 |
| 37.6363636 | 1.905262677 | 2.613077218 | 2.231277324 |
| 38.3636364 | 1.903608223 | 2.604461965 | 2.226628666 |
| 39.0909091 | 1.901149081 | 2.593593312 | 2.220542173 |
| 39.8181818 | 1.897886019 | 2.580662423 | 2.213098084 |
| 40.5454545 | 1.893811306 | 2.565875303 | 2.204378293 |
| 41.2727273 | 1.888910167 | 2.549449243 | 2.194465902 |
| 42.0 | 1.883162224 | 2.531609402 | 2.183444799 |
| 42.7272727 | 1.876543032 | 2.512585464 | 2.17139926 |
| 43.4545455 | 1.869025779 | 2.492608297 | 2.158413575 |
| 44.1818182 | 1.8605832 | 2.471906558 | 2.144571709 |
| 44.9090909 | 1.851189775 | 2.45070322 | 2.129956981 |
| 45.6363636 | 1.840824171 | 2.429212002 | 2.114651785 |
| 46.3636364 | 1.829471908 | 2.40763378 | 2.098737326 |
| 47.0909091 | 1.817128103 | 2.386153072 | 2.082293401 |
| 47.8181818 | 1.803800135 | 2.364934788 | 2.065398192 |
| 48.5454545 | 1.789509965 | 2.344121462 | 2.048128101 |
| 49.2727273 | 1.774295891 | 2.323831223 | 2.030557606 |
| 50.0 | 1.758213466 | 2.304156723 | 2.012759145 |
| 50.7272727 | 1.741335442 | 2.285165178 | 1.994803027 |
| 51.4545455 | 1.723750686 | 2.266899561 | 1.976757363 |
| 52.1818182 | 1.705562128 | 2.249380853 | 1.958688029 |
| 52.9090909 | 1.686883971 | 2.232611154 | 1.940658643 |
| 53.6363636 | 1.667838406 | 2.216577355 | 1.922730569 |
| 54.3636364 | 1.648552156 | 2.201255072 | 1.904962938 |
| 55.0909091 | 1.629153115 | 2.186612553 | 1.887412687 |
| 55.8181818 | 1.609767297 | 2.17261433 | 1.87013462 |
| 56.5454545 | 1.590516228 | 2.159224489 | 1.853181478 |
| 57.2727273 | 1.571514848 | 2.146409484 | 1.836604033 |
| 58.0 | 1.552869893 | 2.134140499 | 1.820451189 |
| 58.7272727 | 1.534678724 | 2.122395428 | 1.804770098 |
| 59.4545455 | 1.517028509 | 2.111160516 | 1.789606295 |
| 60.1818182 | 1.499995669 | 2.100431798 | 1.775003831 |
| 60.9090909 | 1.4836455 | 2.090216384 | 1.761005432 |
| 61.6363636 | 1.468031882 | 2.08053371 | 1.74765266 |
| 62.3636364 | 1.453197003 | 2.07141681 | 1.734986081 |
| 63.0909091 | 1.439171043 | 2.062913685 | 1.723045455 |
| 63.8181818 | 1.42597177 | 2.055088813 | 1.711869923 |
| 64.5454545 | 1.413604026 | 2.048024841 | 1.701498211 |
| 65.2727273 | 1.402059091 | 2.041824467 | 1.69196884 |
| 66.0 | 1.391313947 | 2.03661252 | 1.683320351 |
| 66.7272727 | 1.381330494 | 2.032538193 | 1.675591533 |
| 67.4545455 | 1.372054796 | 2.029777369 | 1.668821672 |
| 68.1818182 | 1.363416488 | 2.028534933 | 1.663050803 |
| 68.9090909 | 1.355328512 | 2.029046931 | 1.658319981 |
| 69.6363636 | 1.347687402 | 2.031582382 | 1.654671563 |
| 70.3636364 | 1.340374316 | 2.036444577 | 1.652149511 |
| 71.0909091 | 1.333257058 | 2.043971681 | 1.650799706 |
| 71.8181818 | 1.326193189 | 2.054536565 | 1.650670288 |
| 72.5454545 | 1.319034267 | 2.068545902 | 1.651812013 |
| 73.2727273 | 1.311631011 | 2.086438791 | 1.654278641 |
| 74.0 | 1.303839047 | 2.10868534 | 1.658127342 |
| 74.7272727 | 1.295524668 | 2.135785855 | 1.663419147 |
| 75.4545455 | 1.286570012 | 2.168271365 | 1.670219421 |
| 76.1818182 | 1.276877083 | 2.206706168 | 1.678598384 |
| 76.9090909 | 1.266370228 | 2.25169296 | 1.688631673 |
| 77.6363636 | 1.254996934 | 2.303880859 | 1.700400957 |
| 78.3636364 | 1.242727071 | 2.363976434 | 1.713994606 |
| 79.0909091 | 1.229550899 | 2.432757678 | 1.729508424 |
| 79.8181818 | 1.21547627 | 2.511090838 | 1.747046458 |
| 80.5454545 | 1.200525457 | 2.599950042 | 1.766721884 |
| 81.2727273 | 1.184731956 | 2.700439852 | 1.788657985 |
| 82.0 | 1.168137532 | 2.813821052 | 1.812989238 |
| 82.7272727 | 1.150789662 | 2.941540212 | 1.839862513 |
| 83.4545455 | 1.132739419 | 3.085263815 | 1.869438403 |
| 84.1818182 | 1.11403981 | 3.246917982 | 1.901892713 |
| 84.9090909 | 1.094744514 | 3.42873509 | 1.937418109 |
| 85.6363636 | 1.07490697 | 3.633308915 | 1.976225968 |
| 86.3636364 | 1.054579739 | 3.86366024 | 2.01854844 |
| 87.0909091 | 1.03381408 | 4.123315369 | 2.064640764 |
| 87.8181818 | 1.012659698 | 4.416400501 | 2.114783865 |
| 88.5454545 | 0.991164591 | 4.747755626 | 2.16928727 |
| 89.2727273 | 0.969375 | 5.123072466 | 2.228492399 |
| 90.0 | 0.947335398 | 5.549062135 | 2.292776262 |
Figure 2.
Age-varying effects of parental alcoholism on lifetime persistent depressive disorder for respondents aged 18–90 years, National Epidemiologic Survey on Alcohol and Related Conditions, Wave III, 2012–2013. Age-varying effects are presented as odds ratios (ORs) across ages; the solid line represents the OR point estimates, and the surrounding shading represents 95% confidence intervals. The horizontal line represents an OR of 1.00.
| Age | Parental Alcoholism Lower Limit | Parental Alcoholism Upper Limit | Parental Alcoholism Estimate (Odds Ratio) |
|---|---|---|---|
| 18.0 | 2.121333968 | 6.551176806 | 3.727899394 |
| 18.7272727 | 2.075574017 | 5.860781704 | 3.487762352 |
| 19.4545455 | 2.029848789 | 5.283819956 | 3.274958861 |
| 20.1818182 | 1.984035647 | 4.800238575 | 3.086072657 |
| 20.9090909 | 1.938049696 | 4.39400751 | 2.91818521 |
| 21.6363636 | 1.891863229 | 4.052213687 | 2.768796503 |
| 22.3636364 | 1.84552654 | 3.764360941 | 2.635759478 |
| 23.0909091 | 1.799186017 | 3.521828612 | 2.517225614 |
| 23.8181818 | 1.753093756 | 3.317455994 | 2.411599342 |
| 24.5454545 | 1.707603271 | 3.145230146 | 2.317499792 |
| 25.2727273 | 1.663149306 | 3.000060743 | 2.233729828 |
| 26.0 | 1.620212854 | 2.877621024 | 2.159249539 |
| 26.7272727 | 1.579278657 | 2.774236703 | 2.093153796 |
| 27.4545455 | 1.540794475 | 2.686804367 | 2.034653121 |
| 28.1818182 | 1.505138875 | 2.612721855 | 1.98305553 |
| 28.9090909 | 1.4726045 | 2.549829007 | 1.937753769 |
| 29.6363636 | 1.443395174 | 2.496351313 | 1.898215329 |
| 30.3636364 | 1.417631989 | 2.450842872 | 1.86397244 |
| 31.0909091 | 1.395365259 | 2.412132959 | 1.834613456 |
| 31.8181818 | 1.376588712 | 2.379277958 | 1.80977545 |
| 32.5454545 | 1.361253018 | 2.351518978 | 1.789137308 |
| 33.2727273 | 1.349275107 | 2.328241584 | 1.77241034 |
| 34.0 | 1.34054929 | 2.308950615 | 1.759335701 |
| 34.7272727 | 1.334956119 | 2.293250066 | 1.749682316 |
| 35.4545455 | 1.332367535 | 2.280824388 | 1.74324306 |
| 36.1818182 | 1.332650157 | 2.271423676 | 1.739831348 |
| 36.9090909 | 1.335667115 | 2.264852012 | 1.739278112 |
| 37.6363636 | 1.341277836 | 2.260956984 | 1.741428003 |
| 38.3636364 | 1.349333336 | 2.259616451 | 1.746131668 |
| 39.0909091 | 1.359678241 | 2.260738268 | 1.753247453 |
| 39.8181818 | 1.372151379 | 2.264258285 | 1.76264152 |
| 40.5454545 | 1.386584443 | 2.270136172 | 1.77418587 |
| 41.2727273 | 1.402800706 | 2.278351648 | 1.787756499 |
| 42.0 | 1.420613986 | 2.288900855 | 1.803231701 |
| 42.7272727 | 1.439825989 | 2.301790321 | 1.820488266 |
| 43.4545455 | 1.46021974 | 2.3170262 | 1.839393214 |
| 44.1818182 | 1.481565837 | 2.334616571 | 1.859808634 |
| 44.9090909 | 1.503626278 | 2.354567875 | 1.881592446 |
| 45.6363636 | 1.52615736 | 2.376878206 | 1.904597114 |
| 46.3636364 | 1.548913488 | 2.401529913 | 1.928668471 |
| 47.0909091 | 1.571651669 | 2.428481794 | 1.953644662 |
| 47.8181818 | 1.594132997 | 2.457658161 | 1.979351907 |
| 48.5454545 | 1.616121257 | 2.488935549 | 2.005597579 |
| 49.2727273 | 1.637394377 | 2.522142752 | 2.032176755 |
| 50.0 | 1.657749164 | 2.557057044 | 2.058873278 |
| 50.7272727 | 1.677002996 | 2.593401109 | 2.085459525 |
| 51.4545455 | 1.694993838 | 2.630842419 | 2.111696401 |
| 52.1818182 | 1.711578621 | 2.668995055 | 2.13733359 |
| 52.9090909 | 1.726627828 | 2.707421364 | 2.162107553 |
| 53.6363636 | 1.740019732 | 2.745634607 | 2.185739782 |
| 54.3636364 | 1.751641031 | 2.783109656 | 2.20794227 |
| 55.0909091 | 1.761383135 | 2.819292424 | 2.228419648 |
| 55.8181818 | 1.769137897 | 2.853610183 | 2.246871139 |
| 56.5454545 | 1.774793588 | 2.885483038 | 2.262992884 |
| 57.2727273 | 1.778231237 | 2.914336455 | 2.276480643 |
| 58.0 | 1.779321666 | 2.939615161 | 2.28703322 |
| 58.7272727 | 1.777923295 | 2.960796734 | 2.294356007 |
| 59.4545455 | 1.773879747 | 2.977405156 | 2.298164203 |
| 60.1818182 | 1.767017848 | 2.989025971 | 2.298186729 |
| 60.9090909 | 1.757146192 | 2.995321497 | 2.294170386 |
| 61.6363636 | 1.74405449 | 2.996045392 | 2.285884165 |
| 62.3636364 | 1.727514047 | 2.99105584 | 2.273123617 |
| 63.0909091 | 1.70727983 | 2.980326367 | 2.255715207 |
| 63.8181818 | 1.683095655 | 2.963954754 | 2.233521741 |
| 64.5454545 | 1.65470297 | 2.942168241 | 2.206448396 |
| 65.2727273 | 1.621849546 | 2.915316254 | 2.174443456 |
| 66.0 | 1.584304069 | 2.883859212 | 2.13750085 |
| 66.7272727 | 1.541875679 | 2.848350404 | 2.095662715 |
| 67.4545455 | 1.494437512 | 2.809410365 | 2.049021287 |
| 68.1818182 | 1.441952684 | 2.767695097 | 1.997720044 |
| 68.9090909 | 1.384500016 | 2.723860792 | 1.941953993 |
| 69.6363636 | 1.322295886 | 2.678528746 | 1.881969059 |
| 70.3636364 | 1.255708302 | 2.632254659 | 1.818060513 |
| 71.0909091 | 1.18525999 | 2.585505937 | 1.750570405 |
| 71.8181818 | 1.111619045 | 2.538649444 | 1.679884243 |
| 72.5454545 | 1.035577447 | 2.491949854 | 1.606426801 |
| 73.2727273 | 0.958018876 | 2.445576339 | 1.530656165 |
| 74.0 | 0.879880702 | 2.399616068 | 1.453057422 |
| 74.7272727 | 0.802113889 | 2.35409105 | 1.374135775 |
| 75.4545455 | 0.725644318 | 2.308975503 | 1.294409113 |
| 76.1818182 | 0.651338299 | 2.264211802 | 1.214400208 |
| 76.9090909 | 0.579974061 | 2.219723938 | 1.134628709 |
| 77.6363636 | 0.512220104 | 2.175428095 | 1.055603148 |
| 78.3636364 | 0.448620673 | 2.13124046 | 0.977813137 |
| 79.0909091 | 0.389588073 | 2.087082647 | 0.901721968 |
| 79.8181818 | 0.335401273 | 2.042885183 | 0.827759803 |
| 80.5454545 | 0.286210024 | 1.99858954 | 0.756317632 |
| 81.2727273 | 0.242043585 | 1.954149091 | 0.687742141 |
| 82.0 | 0.202823099 | 1.909529338 | 0.62233163 |
| 82.7272727 | 0.168376606 | 1.864707633 | 0.560333063 |
| 83.4545455 | 0.138455714 | 1.819672597 | 0.501940305 |
| 84.1818182 | 0.112752985 | 1.774423347 | 0.44729356 |
| 84.9090909 | 0.090919169 | 1.728968626 | 0.396479999 |
| 85.6363636 | 0.07257957 | 1.683325891 | 0.349535504 |
| 86.3636364 | 0.057348922 | 1.637520403 | 0.306447434 |
| 87.0909091 | 0.044844346 | 1.591584332 | 0.267158301 |
| 87.8181818 | 0.034696095 | 1.545555889 | 0.231570192 |
| 88.5454545 | 0.026555975 | 1.499478512 | 0.199549778 |
| 89.2727273 | 0.020103438 | 1.453400077 | 0.170933726 |
| 90.0 | 0.015049499 | 1.407372163 | 0.145534345 |
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Page last reviewed: December 14, 2017