Case #436 – January, 2017

An immigrant from Korea presented with calculi in the intrahepatic biliary passages, cholangitis and early stage cholangiocarcinoma.  Figures AC show what was observed in a hematoxylin and eosin (H & E) stained liver tissue section.  Figure A was captured at 40x magnification; Figures B and C at 200x magnification.  The objects of interest in Figures B and C measured 30 micrometers on average.  What is your diagnosis?  Based on what criteria?

Figure A

Figure B

Figure C

Images presented in the dpdx case studies are from specimens submitted for diagnosis or archiving. On rare occasions, clinical histories given may be partly fictitious.

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