Global Action to Fight Antibiotic Resistance

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Antibiotic Resistance (AR) Spreads Easily Across the Globe

Antibiotic resistance has been identified in all regions of the world. A resistant threat anywhere can quickly become a threat at home. CDC is leading the public health fight as the U.S. continues to take a global One Health approach to combat antibiotic resistance. CDC supports activities in nearly 30 high-burden countries throughout the world to improve antibiotic use, track resistance, and implement infection prevention and control activities. Learn more about how antibiotic resistance can spread across the world.

CDC implements activities outlined in the U.S. National Action Plan for Combating Antibiotic-Resistant Bacteria, released in 2015 and 2020. These activities are funded through CDC antibiotic resistance investments, collectively known as CDC’s Antibiotic Resistance (AR) Solutions Initiative. Through these investments, CDC is transforming how the nation combats antibiotic resistance.

CDC Activities

Building Local, Regional, & National Capacity

  • Enhancing laboratory capacity through CDC’s AR Lab Networks to detect and report antibiotic resistance with global health implications
  • Establishing and strengthening national tracking systems to respond rapidly to outbreaks, identify emerging pathogens, and track trends

Collaborating with Global Partners

  • Contributing to the development and implementation of national action plans to address resistance
  • Implementing healthcare programs to prevent the spread of resistance, including infection prevention and control programs; water, sanitation, and hygiene programs; and antibiotic stewardship programs
  • Offering CDC infection control experts for technical assistance globally

Additional Work in Progress

  • Establishing “learning laboratories” to develop or test innovative, cost-effective solutions for containing urgent antibiotic-resistant germs
  • Improving international collaboration and capacities for prevention, surveillance, and infection control

Examples of CDC Activities in Action

  • Experts are working throughout Latin America to implement national policy, guidelines, and tools to strengthen infection prevention and control capacities to decrease the burden of healthcare-associated infections and contain resistance threats when they are detected in healthcare facilities
  • Experts in several countries have developed infection prevention and control resources and a framework to help estimate the cost-effectiveness of interventions
  • CDC co-led The Antimicrobial Resistance Challenge, a yearlong effort by the U.S. government resulting in more than 350 organizations across the globe committing to take actions that will slow antibiotic resistance