Case #258 – August, 2009

A biopsy was performed on a 23-year-old woman with no known travel history, presenting with a perianal ulcer. The specimen was preserved in formalin and sent to a pathology lab for work-up. Figures A and B show what was observed at 500x magnification from a section of the tissue, stained with hematoxylin and eosin (H&E). What is your diagnosis? Based on what criteria?

Figure A

Figure B

Images presented in the DPDx case studies are from specimens submitted for diagnosis or archiving. On rare occasions, clinical histories given may be partly fictitious.

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