Case #225 – April, 2008

An 8-year-old child was taken to a hospital with fever, hepatomegaly, and persistent cough. The parents told the physician that the child commonly eats dirt, even though they have tried to discourage the habit. A series of tests were conducted, including a liver biopsy. A section made from the biopsy was stained with hematoxylin and eosin (H&E). The following images show what was observed in the specimen. Figures A, B, and C were taken at 200x magnification; Figure D was taken at 1000x oil magnification. The structures shown in Figure D were approximately 57 micrometers long by 32 micrometers wide. What is your diagnosis? Based on what criteria?

Figure A

Figure B

Figure C

Figure D

Images presented in the DPDx case studies are from specimens submitted for diagnosis or archiving. On rare occasions, clinical histories given may be partly fictitious.

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