Evidence to Recommendations Frameworks

The following are the Evidence to Recommendations (EtR) frameworks that describe information considered in moving from evidence to ACIP vaccine recommendations.

The purpose of EtR frameworks is to help panels making recommendations move from evidence to decisions, and to provide transparency around the impact of additional factors on deliberations when considering a recommendation. These tables accompany ACIP recommendations published in the Morbidity and Mortality Weekly Reports (MMWR).

List of Evidence to Recommendations Framework Tables

Listed in most recently published order.

• EtR Framework for a Universal Hepatitis B (HepB) Vaccination Strategy in Adults
  Linked from MMWR; April 1, 2022 / 71(13);477–483
• EtR Framework for use of PreHevbrio Hepatitis B (HepB) Vaccine in Adults
  Linked from MMWR; April 1, 2022 / 71(13);477–483
• EtR Framework for Moderna COVID-19 Vaccine
  Linked from MMWR; March 18, 2022 / 71(11);416–421
• EtR Framework for PCV20 Use Among Adults 19-64 Years Old
  Linked from MMWR; January 28, 2022 / 71(4);109–117
• EtR Framework for PCV20 Use Among Adults ≥65 Years Old
  Linked from MMWR; January 28, 2022 / 71(4);109–117
• EtR Framework for PCV15 Use Among Adults 19-64 Years Old
  Linked from MMWR; January 28, 2022 / 71(4);109–117
• EtR Framework for PCV15 Use Among Adults ≥65 Years Old
  Linked from MMWR; January 28, 2022 / 71(4);109–117
• EtR Framework for Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged ≥19 Years
  Linked from MMWR; January 21, 2022 / 71(3);80–84
• EtR Framework for Dengvaxia
  Linked from MMWR; December 17, 2021 / 70(6);1–16
• EtR Framework for Use of an Additional COVID-19 Vaccine Dose in Immunocompromised People
  Linked from MMWR; October 29, 2021 / 70(44)
• EtR Framework for Use of COVID-19 Vaccine Booster Doses
  Linked from MMWR; October 29, 2021 / 70(44)
• EtR Framework for Use of Janssen COVID-19 Vaccine under an Emergency Use Authorization
  Linked from MMWR; March 2, 2021 / 70(9);329–332
• EtR Framework for Use of rVSVΔG-ZEBOV-GP Ebola vaccine for persons in the U.S. population who are at potential occupational risk of exposure to Ebola virus
  Linked from MMWR; January 8, 2021 / 70(1);1–12
• EtR Framework for Use of Moderna COVID-19 Vaccine under an Emergency Use Authorization
  Linked from MMWR; January 1, 2021 / 69(5152);1653-1656
• EtR Framework for Use of Pfizer-BioNTech COVID-19 Vaccine under an Emergency Use Authorization
  Linked from MMWR; December 18, 2020 / 69(50);1922-1924
• EtR Framework for MenACWY-TT (MenQuadfi) Meningococcal Vaccine
  Linked from MMWR; September 25, 2020 / 69(9);1–41
• EtR Framework for Serogroup B Meningococcal Vaccine Booster Dose
  Linked from MMWRexternal icon; September 25 / 69(9);1–41
• EtR Framework for Serogroup B Meningococcal Vaccine Booster Dose During an Outbreak
  Linked from MMWR; September 25 / 69(9);1–41
• EtR Framework for Hepatitis A Vaccine Catch-up
  Linked from MMWR; July 3, 2020 / 69(5);1–38
• EtR Framework for Hepatitis A Vaccine for Persons With HIV
  Linked from MMWR; July 3, 2020 / 69(5);1–38
• EtR Framework for Tdap Vaccines in Adolescents and Adults
  Linked from MMWR; January 24, 2020 / 69(3);77–83
• EtR Framework for PCV13 use among adults ≥65 years old
  Linked from MMWR; November 22, 2019 / 68(46);1069–75
• EtR Framework for HPV Vaccination of Adults, Ages 27 through 45 years
  Linked from MMWR; August 16, 2019 / 68(32);698–702
• EtR Framework for HPV Vaccination Harmonization across Genders, Ages 22 through 26 years
  Linked from MMWR; August 16, 2019 / 68(32);698–702
• EtR Framework for Japanese Encephalitis Vaccine
  Linked from MMWR; July 19, 2019 / 68(2);1–33