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Reducing the Burden of HPV-associated Cancer and Disease through Vaccination in the US

Presented on .

This session of Grand Rounds explored the burden of human papillomavirus (HPV) -associated cancer and disease in the United States and prevention through HPV vaccination.

HPV is the most common sexually transmitted infection in the United States. There are more than 40 HPV types, some of which cause cancers and others which cause genital warts. Each year, there are an estimated 26,000 HPV-attributable cancers in the United States. About 17,000 occur in women, most of which are cervical cancers, and about 9,000 occur in men, most of which are oropharyngeal cancers. CDC estimates that $8 billion are spent each year on direct medical costs for preventing and treating HPV-associated disease. Currently available HPV vaccines prevent infection from the HPV types that cause about 70% of cervical cancers and the majority of other HPV-attributable cancers. HPV vaccine has been recommended for routine vaccination of 11-12 year-old girls since 2006 and for 11-12 year-old boys since 2011.

This session also provided more insight about the HPV vaccination program and how CDC, state and local health departments, and health care providers are working together to achieve high vaccination levels and reduce the substantial burden of HPV-associated disease.

Beyond the Data

Lauri E. Markowitz, MD, highlights how providers can help:

  • Send reminders to parents and patients that they need to come back for the next vaccine
  • Arrange for “quick visits” – come in, get vaccine and leave – no appointment necessary
  • Let parents and teens know that this is an anti-cancer vaccine – safe and effective
Presented By
CAPT Mona Saraiya, MD, MPH
Medical Officer and Assistant Director for Global Cancer,
Division of Cancer Prevention and Control

National Center for Chronic Disease Prevention and Health Promotion, CDC
CAPT Eileen F. Dunne, MD, MPH
Medical Epidemiologist, Epidemiology and Statistics Branch,
Division of STD Prevention

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC
Shannon Stokley, MPH
Acting Associate Director of Science, Immunization Services Division
Team Lead, Adolescent Vaccination Team

National Center for Immunization and Respiratory Diseases, CDC
Amy Middleman, MD, MSEd, MPH
Assistant Professor, Adolescent Medicine Section
Baylor College of Medicine
Lauri E. Markowitz, MD
Team Lead, Epidemiology and Statistics Branch, Division of STD Prevention
National Center for HIV, Viral Hepatitis, STD and TB Prevention, CDC
Facilitated By
Tanja Popovic, MD, PhD
Scientific Director
John Iskander, MD, MPH
Deputy Scientific Director
Susan Laird, MSN, RN
Communications Director
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Page last reviewed: January 28, 2018
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