Registry Plus Software Programs for Cancer Registries

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Registry Plus is a suite of publicly available free software programs for collecting and processing cancer registry data. The Registry Plus suite can be used separately or together for routine or special data collection. These software programs, compliant with national standards, are made available by CDC to implement the National Program of Cancer Registries, established by Public Law 102-515.

Registry Plus Components

Abstract Plus

A cancer data collection tool that is used to summarize medical records into an electronic report of cancer diagnosis and treatment.

Current version: 6.0 with NAACCR Version 23, released in April 2023.

CRS Plus and TLC Plus

CRS Plus is the main central registry database program, and TLC Plus is an automated tumor linkage and consolidation function.

Current version: 4.6 with NAACCR Version 23, released in April 2023.

Link Plus

A standalone probabilistic record linkage program that can detect duplicates in a cancer registry database and link a cancer registry file with external files.

Current version: 2.0, released in June 2007.

Prep Plus

A program for the central cancer registry that receives NAACCR-formatted abstracts and incorporates them into the central database.

Current version: 5.4, released in April 2023.

Web Plus

Collects cancer data securely over the public Internet to support online abstracting, file upload and download, and follow-back efforts.

Current version: 3.11, released in March 2023.

Web Plus Admin Tool

Allows administrators to export abstracts and uploaded files out of Web Plus, as well as to run edits on uploaded files.

Current version: 7.0, released in March 2023.

eMaRC Plus

Receives and processes HL7 files from pathology laboratories, and reports from physician offices in HL7 CDA format.

Current version: 9, including AJCC TNM 9th edition, released in March 2023.

Exchange Plus
Formerly known as XMLExchangePlus

A tool for reading and writing data exchange files formatted according to the NAACCR XML Data Exchange Standard Implementation Guide.

Current version: 2.5, released in September 2023.

Utility Programs

Small programs that perform a variety of useful functions for Registry Plus programs. They are implemented as dynamic link libraries (DLLs).

Current version: 1.0.0.7, released in August 2023.

Hardware Requirements

Registry Plus programs work with 32- and 64-bit Microsoft® Windows® operating systems on x86-compatible processors. For complete hardware requirements, please see Registry Plus Central Registry Tools Systems and IT Personnel Requirements. [PDF-379KB]

Technical Support

In the United States

Central cancer registries are the primary intended users of Registry Plus. CDC helps states set up the software and perform basic customization. Periodic software updates and problem solving are also provided to the extent of available resources. Our support is provided exclusively by telephone and e-mail. CDC is not staffed to provide on-site services, nor can we support hospitals, clinics, laboratories, or other private users.

Some components of Registry Plus—Abstract Plus, for example—are intended for redistribution after customization. A central registry or other institution redistributing Registry Plus software should provide all support to end users and develop expertise in using the software among its own staff. Other users of Registry Plus software should contract, hire, or develop capability independently to understand and maintain the software applications. Contact your central cancer registry.

Non-NPCR organizations should refer to the Policy and Letter of Agreement for Use of CDC-Developed Software by Users External to the National Program of Cancer Registries. [PDF-13KB]

Outside the United States

The Registry Plus Development group is funded primarily to support NPCR-funded central cancer registries, and cannot offer implementation support for Registry Plus products to other countries. However, you are free to download the programs and implement them using other resources.

For more information, please refer to the Policy and Letter of Agreement for Use of CDC-Developed Software by Users External to the National Program of Cancer Registries. [PDF-13KB]

Please note that data items and codes in Abstract Plus are in English, and are based on North American Assocation of Central Cancer Registries (NAACCR) Standards for Cancer Registries, Volume II, Data Standards and Data Dictionary.

Suggested Citation

Registry Plus, a suite of publicly available software programs for collecting and processing cancer registry data. Atlanta (GA): U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion; 2023. Available at: https://www.cdc.gov/cancer/npcr/. Accessed month/day/year.

Data Flow Diagrams

Diagrams show the flow of data within the Registry Plus software suite and the flow of data from reporting sources to Registry Plus.

Frequently Asked Questions

Answers to questions often asked about Registry Plus software.