Personal Care and Consumer Product Chemicals (PCCPCs)
Diagnostics and Chemical Markers of Exposure
The Organic Analytical Toxicology Branch develops and performs unique laboratory tests to measure organic environmental chemicals in people. Examples of available laboratory tests are shown in the table above. It lists the most common names for these chemicals, and their Chemical Abstracts Service (CAS) Registry Numbers. Many of the chemicals, however, go by alternative names. Please visit the National Library of Medicine ChemID database websiteexternal icon and enter the chemical’s CAS Number. The page displayed after this search will include the chemical’s structure, and alternative names.
Laboratory Methods Panels
CDC’s laboratory methods are intended to evaluate population exposures and to support states in situations considered a public health concern. Please see the “Methods’ Access” tab in the tables found after clicking on each of the listed chemicals for additional information regarding these methods. Currently, CDC’s Organic Analytical Toxicology Branch does not have the capability of generating pilot or preliminary results in support of proposals to obtain public or private funds for a larger project.
CAS No. 80-05-7
CAS No. 1333-16-0
CAS No. 80-09-1
CAS No. 131-57-7
CAS No. 120-83-2
CAS No. 583-78-8
CAS No. 99-76-3
CAS No. 120-47-8
CAS No. 94-13-3
CAS No. 94-26-8
CAS No. 3380-34-5
CAS No. 101-20-2
Laboratory Method: https://www.cdc.gov/nchs/data/nhanes/nhanes_13_14/EPHPP_H_MET.pdfpdf icon
Trends in Exposure to Chemicals in Personal Care and Consumer Products
Calafat AM, Valentin-Blasini L, Ye X. Curr Environ Health Rep. 2015 Dec;2(4):348-55. doi: 10.1007/s40572-015-0065-9.
Exposure to select phthalates and phenols through use of personal care products among Californian adults and their children
Philippat C, Bennett D, Calafat AM, Picciotto IH. Environ Res. 2015 Apr 27;140:369-376
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724203/pdf/nihms722609.pdfpdf iconexternal icon
Personal care product use and urinary phthalate metabolite and paraben concentrations during pregnancy among women from a fertility clinic
Braun JM, Just AC, Williams PL, Smith KW, Calafat AM, Hauser R. J Expo Sci Environ Epidemiol. 2014 Sep-Oct;24(5):459-66. doi: 10.1038/jes.2013.69.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016195/pdf/nihms571646.pdfpdf iconexternal icon
Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study
Nassan FL, Coull BA, Gaskins AJ, Williams MA, Skakkebaek NE, Ford JB, Ye X, Calafat AM, Braun JM, Hauser R.
Environ Health Perspect. 2017 Aug 18;125(8):087012. doi: 10.1289/EHP1374.
Patterns, Variability, and Predictors of Urinary Triclosan Concentrations during Pregnancy and Childhood
Stacy SL, Eliot M, Etzel T, Papandonatos G, Calafat AM, Chen A, Hauser R, Lanphear BP, Sathyanarayana S, Ye X, Yolton K, Braun JM. Environ Sci Technol. 2017 Jun 6;51(11):6404-6413. doi: 10.1021/acs.est.7b00325. Epub 2017 May 25.
Urinary Bisphenol A (BPA) Concentrations among Workers in Industries that Manufacture and Use BPA in the USA
Hines CJ, Jackson MV, Deddens JA, Clark JC, Ye X, Christianson AL, Meadows JW, Calafat AM. Ann Work Expo Health. 2017 Mar 1;61(2):164-182. doi: 10.1093/annweh/wxw021.
Biomonitoring Factsheets: Bisphenol A (BPA), Benzophenone-3 (BP-3), Triclosan, Parabens
National Report on Human Exposure to Environmental Chemicals
Peer-Reviewed Biomonitoring Articles
CDC’s laboratory methods are intended to evaluate population exposures and to support states in situations considered a public health concern. CDC does not provide individual health care or assessment unless as part of a broader public health investigation requested by federal or state agencies, such as a health department. Currently, CDC’s Organic Analytical Toxicology Branch does not have the capability of generating pilot or preliminary results in support of proposals to obtain public or private funds for a larger project.
Detecting levels of an environmental chemical in a person’s blood or urine does not necessarily mean the chemical will cause adverse health effects or disease. Advances in analytical methods enable CDC to measure very low levels of environmental chemicals in people, but research studies of varying levels of exposure are needed to determine if specific levels cause health effects. Consulting a clinician with a toxicological background to assist with the interpretation of results is recommended.
Samples to be tested should be processed through a state health department laboratory, and should conform to the laboratory’s reporting procedures. These laboratory methods often require that the sample be collected by a particular method, or sometimes with particular pre-screened collection devices, to minimize external contamination. Following the correct sample collection protocol is necessary for accurate sample measurement. Please contact the laboratory that will be analyzing the sample to learn the sample collection instructions before collecting the samples.
Contact DLSLab@cdc.gov for more information or questions about these laboratory methods.