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HIV Risk Reduction (RR) Efficacy Review: Efficacy Criteria
The Prevention Research Synthesis (PRS) Project risk reduction efficacy criteria are used to determine if an HIV behavioral intervention is an Evidence-Based Intervention (EBI). Based on the overall quality of the study, evidence-based risk reduction behavioral interventions are classified as either best-evidence or good-evidence.
Evidence-Based Interventions (EBIs)
Best Evidence
- Clear description of key aspects
- Prospective study design
- Appropriate and concurrent comparison arm
- Random or minimally biased assignment to study arms
- Shown to have significant and positive evidence of efficacy.
These interventions are scientifically rigorous and provide the strongest evidence of efficacy.
Evidence-Based Interventions (EBIs)
Good Evidence
- Clear description of key aspects
- Prospective or quasi-prospective study design
- Appropriate/concurrent comparison arm or historical comparison
- Random, minimally biased, or moderately biased allocation to study arms
- Shown to have significant and positive evidence of efficacy
These interventions are scientifically sound and provide sufficient evidence of efficacy.
