A protocol gives a step-by-step plan for a systematic review. The protocol details the rationale, hypotheses or research questions, search strategy, and planned methods of the review. The protocol is usually developed prior to the start of a review and can be submitted to a public registry.

Crepaz, N., Mullins, M., Higa, D., Collins, C., Peters, O. Identification of effective strategies for improving engagement to HIV prevention and care among transgender persons in the United States: A systematic review. PROSPERO 2022 CRD42022364101 Available from:

Kamitani, E., Mizuno, Y., Collins, C., DeLuca, J. B., & Smith, D. K. Alternative PrEP care delivery models to improve PrEP care: Systematic review. PROSPERO: International prospective register of systematic reviews (CRD42022311747). 2022. Available from:

Kamitani, E., Higa, D., Crepaz, N., Wichser, M., & Mullins, M.Evidence-based and evidence-informed interventions for HIV pre-exposure prophylaxis (PrEP) use and persistence: A systematic review. PROSPERO 2021 CRD42021256460. Available from:

Crepaz, N., Higa, D., Mullins, M., Salabarria-Pena, Y., & Gunn, J. Systematic review of social and structural factors associated with HIV testing among Hispanic/Latino men who have sex with men (MSM) in the United Statesexternal icon. PROSPERO 2020 CRD42020175063. Available from:

McDonald, C., Barham, T., Mullins, M., Carter, J., Sipe, T., Becasen, J., Adegbite-Johnson, A., Arthur, B., Gaines, M., & Prather, C. Racism and HIV among African-Americans: A Systematic Reviewexternal icon. PROSPERO 2020 CRD42020160143. Available from:

Nji, M. A. M., Gunn, J., Higa, D., Mullins, M. Koenig, L. J., Denard, C. L., & Sipe. T. A. Assessing the effectiveness of data-to-care activities for improving HIV care outcomes: A systematic reviewexternal icon. PROSPERO 2020 CRD42020173095. Available from:

Kamitani, E., Johnson, A. H., Wichser, M., Mizuno, Y., DeLuca, J. B., & Higa, D. H. (2019). Mapping the study topics and characteristics of HIV pre-exposure prophylaxis research literature: A protocol for a scoping reviewexternal iconBMJ Open, 9(5), e024212. doi: 10.1136/bmjopen-2018-024212

Kamitani, E., Mizuno, Y., Wichser, M. E., Adegbite-Johnson, A. H., DeLuca, J. B., & Higa D. H. (2019). Systematic review of predictors for HIV pre-exposure prophylaxis uptake in key populations identified in national HIV prevention goalsexternal icon. PROSPERO 2019 CRD42019112390. Available from:

Mizuno, Y., Kamitani, E., Crepaz,N., Leighton, C., Gelaude, D., DeLuca, J., Wichser, M., & Smith, D. Systematic review of correlates of HIV pre-exposure prophylaxis (PrEP) prescription by health care providers in the United States (U.S.)external icon. PROSPERO 2019 CRD42019138889. Available from:

Becasen, J., Denard, C., Kamitani, E., Mullins, M., & Higa, D. (2018). HIV care outcomes among transgender persons with HIV in the U.S.: A systematic review and meta-analysisexternal icon. PROSPERO Protocol 2018 CRD42018079564. Available from:

Malekinejad, M., Horvathm H., Kahn, J.G., Barker, E., Lyles, C., Sipe, T., Tailor, A., Brooks, J., Purcell, D., Gift, T., Chesson, H., Ridpath, A., Bernstein, K., & DeLuca, J. Risk of HIV transmission and acquisition among HIV high-risk populations infected with other sexually transmitted infectionsexternal icon. PROSPERO: International prospective register of systematic reviews. 2018. CRD42018084299. Available from:

Rooks-Peck, C., Barham, T., DeLuca, J. B., Flores, S., Herron, A., Higa, D., Jeffries, W. L., IV, McCree, D., & Ross, L. (2018). Effectiveness of HIV stigma interventions for men who have sex with men (MSM) living with and without HIV: A systematic reviewexternal icon. PROSPERO Protocol 2018 CRD42018091305. Available from:

Semaan, S., Johnson, W., Rivadeneira, N., Adegbite, A., Neumann, M., Mullins, M., Rooks-Peck, C., Higa, D., & Sipe, T. (2017). Review of quantitative reviews that included meta-analysis results of HIV prevention interventions for persons who use drugsexternal icon. PROSPERO Protocol 2017 CRD42017070117. Available from:

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