Structural Interventions (SI) Best Practices Criteria

National HIV prevention goals call for the expansion of targeted efforts to prevent HIV infection using a combination of effective, evidence-based approaches. Structural approaches, or those that do not rely on individual behavior change to alter the environment, can be used to enhance the effectiveness of biomedical and behavioral interventions.  The Structural Interventions (SI) Chapter for the PRS Compendium provides visibility and easy access to evidence-based interventions (EBIs) and evidence-informed interventions (EIs) that are considered structural.

SI Evidence-Based Interventions (S-EBIs)

EB-criteria pdf icon[PDF – 229 KB] evaluate intervention studies that have a comparison group, similar to PRS RR, MA, and LRC evidence-based reviews. Intervention studies that meet EB criteria are considered to be scientifically rigorous and provide the strongest evidence of efficacy.

SI Evidence-Informed interventions (S-EIs)

EI-criteria pdf icon[PDF – 222 KB] evaluate SI studies lacking a comparison group, but for which there are pre-post intervention data. EI criteria are also used for SI studies with a comparison arm that did not meet EB criteria for sample size, but met all other EB criteria. Intervention studies that meet EI criteria also provide some evidence of effectiveness.

Additional details about the SI Chapter or the Prevention Research Synthesis (PRS) Project can be obtained by contacting PRS.