Complete Listing of Risk Reduction Evidence-based Behavioral Interventions
- 2GETHER [PDF – 293 KB] NEW 2023
Best
Intended Population: Young male couples
Year published: 2023
Author: Michael Newcomb
Study years: 2018 – 2020
Structural component: None reported - AMIGAS [PDF – 667 KB]
Best
Intended population: Latina women
Intervention level: Group-level
Year published: 2011
Author: Gina M. Wingood
Study years: 2007 – 2010 - Adapted-Stage Enhanced Motivational Interviewing (A-SEMI) [PDF – 333 KB]
Good
Intended population: High-risk Hispanic/Latino migrant workers
Intervention level: Group-level
Year published: 2013
Author: Jesús Sánchez
Study years: 2008 – 2010 - CARE+ [PDF – 723 KB]
Best
Intended population: HIV clinic patients who are antiretroviral treatment-experienced
Intervention level: Individual-level
Year published: 2014
Author: Ann E. Kurth
Study years: 2006 – 2008 - CHAT [PDF – 200 KB]
Best
Intended population: High risk heterosexual women and their social network
Intervention level: Group-level
Year published: 2011
Author: Melissa A. Davey-Rothwell
Study years: 2005 – 2010 - Choosing Life: Empowerment, Actions, Results (CLEAR) [PDF – 238 KB]
Best
Intended population: Young HIV-positive substance abusers
Intervention level: Individual-level
Year published: 2004
Author: Mary Jane Rotheram-Borus
Study years: 1999 – 2003 - Community Promise [PDF – 236 KB]
Good
Intended population: Underserved populations at risk for HIV infection
Intervention level: Community-level
Year published: 1999
Author: CDC ACDP Research Group
Study years: 1991 – 1994 - Connect 2 [PDF – 915 KB]
Best
Intended population: Drug-involved, HIV-negative concordant, high risk heterosexual couples
Intervention level: Couple-level
Year published: 2011
Author: Nabila El-Bassel
Study years: 2005 – 2010 - Couples HIV Intervention Program (CHIP) [PDF – 266 KB]
Good
Intended population: Transgender women and their primary cisgender male partners
Intervention level: Couple-level
Year published: 2017
Author: Don Operario
Study years: 2013 – 2014 - Drug Users Intervention Trial (DUIT) [PDF – 327 KB]
Good
Intended population: Young HIV-negative and Hepatitis C-negative injection drug users (IDUs)
Intervention level: Group-level
Year published: 2007
Author: Richard S. Garfein
Study years: 2002 – 2004 - Eban [PDF – 953 KB]
Best
Intended population: African American HIV serodiscordant heterosexual couples
Intervention level: Couple-level
Year published: 2010
Author: Nabila El-Bassel
Study years: 2003 – 2007 - ECHO [PDF – 663 KB]
Best
Intended population: High-risk HIV-negative episodic substance using MSM
Intervention level: Individual-level
Year published: 2014
Author: Phillip O. Coffin
Study years: 2010 – 2012 - E-WORTH (Empowering African American Women on the Road To Health) New 2023 [PDF – 268 KB]
Best
Intended Population: Black or African American women who use/have used substances and are attending community supervision programs (CSPs)
Intervention level: Individual-level
Year published: 2021
Author: Louisa Gilbert
Study years: 2015 – 2019
Structural Component: None reported - Familias Unidas [PDF – 661 KB]
Best
Intended population: Hispanic or Latino delinquent youth and their primary caregivers
Intervention level: Group-level
Year published: 2012
Author: Guillermo Prado
Study years: 2009 – 2010 - Focus on the Future (FoF) for Black Male Youths [PDF – 656 KB]
Best
Intended population: Sexually active black males aged 15-23 years
Intervention level: Individual-level
Year published: 2014
Author: Richard A. Crosby
Study years: 2010 – 2012 - HealthMpowerment (HMP) [PDF – 267 KB]
Good
Intended population: Young Black men who have sex with men (BMSM) and have access to mobile devices (e.g., smartphone, tablet)
Year published: 2019
Author: Lisa Hightow-Weidman
Study years: 2013 – 2015
Structural component: None reported - Healthy Living Project (HLP) [PDF – 756 KB]
Best
Intended population: HIV-positive persons at risk of transmitting HIV
Intervention level: Individual-level
Year published: 2007
Author: Healthy Living Project Team
Study years: 2000 – 2004 - Healthy Love [PDF – 239 KB]
Good
Intended population: Black women
Intervention level: Group-level
Year published: 2010
Author: Dázon D. Diallo
Study years: 2006 – 2007 - Healthy Relationships [PDF – 234 KB]
Best
Intended population: People living with HIV (HIV+)
Intervention level: Group-level
Year published: 2001
Author: Seth Kalichman
Study years: 1997 – 1998 - HIP Teens [PDF – 235 KB]
Good
Intended population: Low-income, urban, sexually-active adolescent females
Intervention level: Group-level
Year published: 2013
Author: Dianne Morrison-Beedy
Study years: 2004 – 2008 - HIV Internet Sex (HINTS) [PDF – 249 KB]
Best
Intended population: Sexual minority (gay and bisexual) men with HIV/AIDS
Intervention level: Group-level
Year published: 2018
Author: Dean G. Cruess
Study years: 2012 – 2014 - HIV Self-Testing [PDF – 275 KB
Best
Intended population: Men who have sex with men (MSM) without HIV
Year published: 2018
Author: David Katz
Study years: 2010 – 2014
Structural component: Access, Physical Structure - HOLA [PDF – 289 KB] NEW 2023
Best
Intended population: Immigrant Hispanic/Latino gay, bisexual, and other men who have sex with men (GBMSM) who speak Spanish; Immigrant Hispanic/Latina transgender women (TW) who speak Spanish
Year published: 2020
Author: Scott Rhodes
Study years: 2011 – 2018
Structural component: None reported - HOLA en Grupos [PDF – 943 KB]
Best
Intended population: Hispanic/Latino men who have sex with men (MSM)
Intervention level: Group-level
Year published: 2017
Author: Scott D. Rhodes
Study years: 2012 – 2015 - IMARA (Informed, Motivated, Aware, and Responsible about AIDS) [PDF – 307 KB]
Best
Intended population: Black or African American adolescent girls
Year published: 2020
Author: Geri Donenberg
Study years: 2012 – 2017
Structural component: None reported - In The Mix [PDF – 663 KB]
Best
Intended population: People living with HIV/AIDS (HIV+)
Intervention level: Group-level
Year published: 2011
Author: Seth Kalichman
Study years: 2005 – 2009 - ISUM [PDF – 259 KB]
Best
Target population: Transgender women (TGW) and men who have sex with men (MSM) who are HIV-negative and not taking pre-exposure prophylaxis (PrEP) who engage in sexual risk behavior
Intervention level: Individual-level
Year published: 2020
Author: Alex Carballo-Diéguez
Study years: 2014 – 2019 - Keep It Up! 2.0 [PDF – 932 KB]
Best
Intended population: HIV-negative young men who have sex with men (MSM)
Intervention level: Individual-level
Year published: 2018
Author: Brian Mustanski
Study years: 2013 – 2015 - LIFT [PDF – 657 KB]
Best
Intended population: HIV-positive adults with childhood sexual abuse (CSA) histories
Intervention level: Group-level
Year published: 2008
Author: Kathleen Sikkema
Study years: 2002 – 2004 - M-Cubed (Mobile Messaging for Men) [PDF – 272 KB]
Best
Intended population: Gay, bisexual, and other men who have sex with men (GBMSM)
Year published: 2022
Author:Patrick Sullivan
Study years: 2018 – 2019
Structural components: None reported - Males of African American Legacy Empowering Self (MAALES) [PDF – 246 KB]
Good
Intended population: Black or African American men who have sex with men and women (MSMW)
Intervention level: Group-level
Year published: 2013
Author: Nina T. Harawa
Study years: 2007 – 2011 - Many Men, Many Voices (3MV) [PDF – 239 KB]
Best
Intended population: Black men who have sex with men (MSM) of HIV-negative or unknown HIV serostatus
Intervention level: Group-level
Year published: 2009
Author: Leo Wilton
Study years: 2005 – 2006 - Mpowerment [PDF – 236 KB]
Good
Intended population: Young MSM
Intervention level: Community-level
Year published: 1996
Author: Susan M. Kegeles
Study years: Not reported - Navigation-Enhanced Case Management (NAV) [PDF – 375 KB]
Good
Intended population: Adults living with HIV, leaving jail, and who have previously used or are currently using substances
Intervention level: Individual-level
Year published: 2018
Author: Janet J. Myers
Study years: 2010 – 2013 - No Excuses/Sin buscar excusas [PDF – 236 KB]
Best
Intended population: High-risk, Latino men who have sex with men (MSM)
Intervention level: Group-level
Year published: 2014
Author: Lydia O’Donnell
Study years: 2008 – 2009 - Options/Opciones Project [PDF – 235 KB]
Good
Intended population: HIV-positive clinic patients
Intervention level: Individual-level
Year published: 2006
Author: Jeffrey D. Fisher
Study years: 2000 – 2003 - Partnership for Health (Loss-Frame Intervention) [PDF – 235 KB]
Good
Intended population: HIV-positive clinic patients
Intervention level: Individual-level
Year published: 2004
Author: Jean L. Richardson
Study years: 1999 – 2000 - Personalized Cognitive Counseling (PCC) [PDF – 245 KB]
Best
Intended population: Men who have sex with men (MSM) who are HIV seronegative and have undergone repeat HIV testing
Intervention level: Individual-level
Year published: 2002
Author: James W. Dilley
Study years: 1997 – 2000 - Popular Opinion Leader (POL) [PDF – 238 KB]
Good
Intended population: Men who frequent gay bars
Intervention level: Community-level
Year published: 1997
Author: Jeffrey A. Kelly
Study years: 1989 – 1991 - Positive Choice: Interactive Video Doctor [PDF – 657 KB]
Best
Intended population: HIV-positive clinic patients
Intervention level: Individual-level
Year published: 2008
Author: Paul Gilbert
Study years: 2003 – 2006 - POWER [PDF – 340 KB]
Best
Intended population: Black men who have sex with men and women (MSMW)
Intervention level: Individual-level
Year published: 2016
Author: M. Isabel Fernandez
Study years: 2008 – 2013 - Prime Time [PDF – 930 KB]
Best
Intended population: Sexually active adolescent females at elevated risk for teen pregnancy and sexually transmitted infections
Intervention level: Individual- and group-level
Year published: 2014
Author: Renee E. Sieving
Study years: 2007 – 2011 - Project IMAGE [PDF – 231 KB]
Good
Intended population: Mexican and African American female adolescents with a history of sexual or physical abuse and sexually transmitted infections (STI)
Intervention level: Group-level
Year published: 2012
Author: Jane D. Champion
Study years: 2005 – 2009 - Project LifeSkills [PDF – 232 KB]
Best
Intended population: Young transgender women
Intervention level: Group-level
Year published: 2018
Author: Robert Garofalo
Study years: 2012 – 2016 - Project RISE [PDF – 915 KB]
Best
Intended population: Black men who have sex with men and women (MSMW)
Intervention level: Individual-level
Year published: 2018
Author: Mary Milnamow
Study years: 2010 – 2012 - Protect & Connect (PACT) [PDF – 276 KB]
Best
Intended population: Men in community supervision who use drugs and their main female sex partners
Intervention level: Couple-level
Year published: 2019
Author: Nabila El-Bassel
Study years: 2013 – 2017 - Project STYLE [PDF – 675 KB]
Best
Intended population: Adolescents (aged 13 – 18 years) in mental health treatment
Intervention level: Group-level
Year published: 2014
Author: Larry K. Brown
Study years: 2003 – 2008 - Reducing the Risk Plus (RTR ) [PDF – 676 KB]
Best
Intended population: Adolescents
Intervention level: Group-level
Year published: 2014
Author: Valerie F. Reyna
Study years: Not reported - Safe in the City [PDF – 230 KB]
Best
Intended population: STD clinic patients
Intervention level: Individual-level
Year published: 2008
Author: Lee Warner
Study years: 2003 – 2005 - SafeTalk [PDF – 237 KB]
Good
Intended population: Sexually active HIV-positive adult clinic patients
Intervention level: Individual-level
Year published: 2010
Author: Carol E. Golin
Study years: 2006 – 2009 - Sister-to-Sister: One-on-One Skills Building [PDF – 243 KB]
Best
Intended population: Inner-city African American female clinic patients
Intervention level: Individual-level
Year published: 2007
Author: John B. Jemmott
Study years: 1993 – 1996 - STRIVE [PDF – 917 KB]
Best
Intended population: HIV-negative injection drug users with Hepatitis C virus (HCV) infection
Intervention level: Group-level
Year published: 2008
Author: Mary H. Latka
Study years: 2002 – 2004 - Strong African American Families-Teen (SAAF-T) [PDF – 258 KB]
Good
Intended population: African American adolescents living in in the rural South and their caregivers
Intervention level: Group-level
Year published: 2012
Author: Steven M. Kogan
Study years: 2007 – 2010 - The Workshop [PDF – 303 KB]
Good
Intended population: People who use drugs (PWUD) (i.e., heroin or cocaine) and experience depressive symptoms living in an urban area with high HIV prevalence and unrecognized HIV infection
Year published: 2017
Author: Karen Tobin
Study years: 2010 – 2012
Structural components: None reported - Think Twice (Pilot) [PDF – 925 KB]
Best
Intended population: High-risk men who have sex with men (MSM)
Intervention level: Individual-level
Year published: 2011
Author: Lisa A. Eaton
Study years: 2009 - Think Twice [PDF – 930 KB]
Best
Intended population: Men who have sex with men (MSM)
Intervention level: Individual-level
Year published: 2018
Author: Lisa A. Eaton
Study years: 2014 – 2015 - Treatment Advocacy Program (TAP) [PDF – 666 KB]
Best
Intended population: HIV-positive sexually active men who have sex with men (MSM) clinic patients
Intervention level: Individual-level
Year published: 2010
Author: David J. McKirnan
Study years: 2004 - TRUST [PDF – 234 KB] NEW 2023
Good
Intended Population: Young Black or African American men who have sex with men (YBMSM) and transgender women (TW)
Year published: 2021
Author: Victoria Frye
Study years: July 2016 – December 2017
Structural component: Access, Physical Structure - Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES) [PDF – 239 KB]
Best
Intended population: African American and Hispanic STD clinic patients
Intervention level: Group-level
Year published: 1995
Author: Lydia O’Donnell
Study years: 1991 – 1994 - Women Involved in Life Learning from Other Women (WiLLOW) [PDF – 227 KB]
Best
Intended population: Sexually-active, female clinic patients living with HIV
Intervention level: Group-level
Year published: 2004
Author: Gina Wingood
Study years: 1997 – 2002 - WORTH [PDF – 757 KB]
Best
Intended population: Drug-involved, high risk female offenders under community supervision
Intervention level: Group-level
Year published: 2014
Author: Nabila El-Bassel
Study years: 2009 – 2012 - Young Men’s Health Project [PDF – 668 KB]
Best
Intended population: High-risk, young gay and bisexual men
Intervention level: Individual-level
Year published: 2014
Author: Jeffrey T. Parsons
Study years: 2007 – 2010
