Complete Listing of Risk Reduction Evidence-based Behavioral Interventions

  • AMIGAS [PDF – 667 KB]
    Best
    Intended population: Latina women
    Intervention level: Group-level
    Year published: 2011
    Author: Gina M. Wingood
    Study years: 2007 – 2010
  • Adapted-Stage Enhanced Motivational Interviewing (A-SEMI) [PDF – 333 KB]
    Good
    Intended population: High-risk Hispanic/Latino migrant workers
    Intervention level: Group-level
    Year published: 2013
    Author: Jesús Sánchez
    Study years: 2008 – 2010
  • CARE+ [PDF – 723 KB]
    Best
    Intended population: HIV clinic patients who are antiretroviral treatment-experienced
    Intervention level: Individual-level
    Year published: 2014
    Author: Ann E. Kurth
    Study years: 2006 – 2008
  • CHAT [PDF – 200 KB]
    Best
    Intended population: High risk heterosexual women and their social network
    Intervention level: Group-level
    Year published: 2011
    Author: Melissa A. Davey-Rothwell
    Study years: 2005 – 2010
  • Choosing Life: Empowerment, Actions, Results (CLEAR) [PDF – 238 KB]
    Best
    Intended population: Young HIV-positive substance abusers
    Intervention level: Individual-level
    Year published: 2004
    Author: Mary Jane Rotheram-Borus
    Study years: 1999 – 2003
  • Community Promise [PDF – 236 KB]
    Good
    Intended population: Underserved populations at risk for HIV infection
    Intervention level: Community-level
    Year published: 1999
    Author: CDC ACDP Research Group
    Study years: 1991 – 1994
  • Connect 2 [PDF – 915 KB]
    Best
    Intended population: Drug-involved, HIV-negative concordant, high risk heterosexual couples
    Intervention level: Couple-level
    Year published: 2011
    Author: Nabila El-Bassel
    Study years: 2005 – 2010
  • Couples HIV Intervention Program (CHIP) [PDF – 266 KB]
    Good
    Intended population: Transgender women and their primary cisgender male partners
    Intervention level: Couple-level
    Year published: 2017
    Author: Don Operario
    Study years: 2013 – 2014
  • Drug Users Intervention Trial (DUIT) [PDF – 327 KB]
    Good
    Intended population: Young HIV-negative and Hepatitis C-negative injection drug users (IDUs)
    Intervention level: Group-level
    Year published: 2007
    Author: Richard S. Garfein
    Study years: 2002 – 2004
  • Eban [PDF – 953 KB]
    Best
    Intended population: African American HIV serodiscordant heterosexual couples
    Intervention level: Couple-level
    Year published: 2010
    Author: Nabila El-Bassel
    Study years: 2003 – 2007
  • ECHO [PDF – 663 KB]
    Best
    Intended population: High-risk HIV-negative episodic substance using MSM
    Intervention level: Individual-level
    Year published: 2014
    Author: Phillip O. Coffin
    Study years: 2010 – 2012
  • Familias Unidas [PDF – 661 KB]
    Best
    Intended population: Hispanic or Latino delinquent youth and their primary caregivers
    Intervention level: Group-level
    Year published: 2012
    Author: Guillermo Prado
    Study years: 2009 – 2010
  • Focus on the Future (FoF) for Black Male Youths [PDF – 656 KB]
    Best
    Intended population: Sexually active black males aged 15-23 years
    Intervention level: Individual-level
    Year published: 2014
    Author: Richard A. Crosby
    Study years: 2010 – 2012
  • HealthMpowerment (HMP) [PDF – 267 KB] NEW 2022
    Good
    Intended population: Young Black men who have sex with men (BMSM) and have access to mobile devices (e.g., smartphone, tablet)
    Year published: 2019
    Author: Lisa Hightow-Weidman
    Study years: 2013 – 2015
    Structural component: None reported
  • Healthy Living Project (HLP) [PDF – 756 KB]
    Best
    Intended population: HIV-positive persons at risk of transmitting HIV
    Intervention level: Individual-level
    Year published: 2007
    Author: Healthy Living Project Team
    Study years: 2000 – 2004
  • Healthy Love [PDF – 239 KB]
    Good
    Intended population: Black women
    Intervention level: Group-level
    Year published: 2010
    Author: Dázon D. Diallo
    Study years: 2006 – 2007
  • Healthy Relationships [PDF – 234 KB]
    Best
    Intended population: People living with HIV (HIV+)
    Intervention level: Group-level
    Year published: 2001
    Author: Seth Kalichman
    Study years: 1997 – 1998
  • HIP Teens [PDF – 235 KB]
    Good
    Intended population: Low-income, urban, sexually-active adolescent females
    Intervention level: Group-level
    Year published: 2013
    Author: Dianne Morrison-Beedy
    Study years: 2004 – 2008
  • HIV Internet Sex (HINTS) [PDF – 249 KB]
    Best
    Intended population: Sexual minority (gay and bisexual) men with HIV/AIDS
    Intervention level: Group-level
    Year published: 2018
    Author: Dean G. Cruess
    Study years: 2012 – 2014
  • HOLA en Grupos [PDF – 943 KB]
    Best
    Intended population: Hispanic/Latino men who have sex with men (MSM)
    Intervention level: Group-level
    Year published: 2017
    Author: Scott D. Rhodes
    Study years: 2012 – 2015
  • IMARA (Informed, Motivated, Aware, and Responsible about AIDS) [PDF – 307 KB] NEW 2022
    Best
    Intended population: Black or African American adolescent girls
    Year published: 2020
    Author: Geri Donenberg
    Study years: 2012 – 2017
    Structural component: None reported
  • In The Mix [PDF – 663 KB]
    Best
    Intended population: People living with HIV/AIDS (HIV+)
    Intervention level: Group-level
    Year published: 2011
    Author: Seth Kalichman
    Study years: 2005 – 2009
  • ISUM [PDF – 259 KB] NEW 2021
    Best
    Target population: Transgender women (TGW) and men who have sex with men (MSM) who are HIV-negative and not taking pre-exposure prophylaxis (PrEP) who engage in sexual risk behavior
    Intervention level: Individual-level
    Year published: 2020
    Author: Alex Carballo-Diéguez
    Study years: 2019 – 2006
  • Keep It Up! 2.0 [PDF – 932 KB]
    Best
    Intended population: HIV-negative young men who have sex with men (MSM)
    Intervention level: Individual-level
    Year published: 2018
    Author: Brian Mustanski
    Study years: 2013 – 2015
  • LIFT [PDF – 657 KB]
    Best
    Intended population: HIV-positive adults with childhood sexual abuse (CSA) histories
    Intervention level: Group-level
    Year published: 2008
    Author: Kathleen Sikkema
    Study years: 2002 – 2004
  • M-Cubed (Mobile Messaging for Men) [PDF – 272 KB] NEW 2022
    Best
    Intended population: Gay, bisexual, and other men who have sex with men (GBMSM)
    Year published: 2022
    Author:Patrick Sullivan
    Study years: 2018 – 2019
    Structural components: None reported
  • Males of African American Legacy Empowering Self (MAALES) [PDF – 246 KB]
    Good
    Intended population: Black or African American men who have sex with men and women (MSMW)
    Intervention level: Group-level
    Year published: 2013
    Author: Nina T. Harawa
    Study years: 2007 – 2011
  • Many Men, Many Voices (3MV) [PDF – 239 KB]
    Best
    Intended population: Black men who have sex with men (MSM) of HIV-negative or unknown HIV serostatus
    Intervention level: Group-level
    Year published: 2009
    Author: Leo Wilton
    Study years: 2005 – 2006
  • Mpowerment [PDF – 236 KB]
    Good
    Intended population: Young MSM
    Intervention level: Community-level
    Year published: 1996
    Author: Susan M. Kegeles
    Study years: Not reported
  • Navigation-Enhanced Case Management (NAV) [PDF – 375 KB]
    Good
    Intended population: Adults living with HIV, leaving jail, and who have previously used or are currently using substances
    Intervention level: Individual-level
    Year published: 2018
    Author: Janet J. Myers
    Study years: 2010 – 2013
  • No Excuses/Sin buscar excusas [PDF – 236 KB]
    Best
    Intended population: High-risk, Latino men who have sex with men (MSM)
    Intervention level: Group-level
    Year published: 2014
    Author: Lydia O’Donnell
    Study years: 2008 – 2009
  • Options/Opciones Project [PDF – 235 KB]
    Good
    Intended population: HIV-positive clinic patients
    Intervention level: Individual-level
    Year published: 2006
    Author: Jeffrey D. Fisher
    Study years: 2000 – 2003
  • Partnership for Health (Loss-Frame Intervention) [PDF – 235 KB]
    Good
    Intended population: HIV-positive clinic patients
    Intervention level: Individual-level
    Year published: 2004
    Author: Jean L. Richardson
    Study years: 1999 – 2000
  • Personalized Cognitive Counseling (PCC) [PDF – 245 KB]
    Best
    Intended population: Men who have sex with men (MSM) who are HIV seronegative and have undergone repeat HIV testing
    Intervention level: Individual-level
    Year published: 2002
    Author: James W. Dilley
    Study years: 1997 – 2000
  • Popular Opinion Leader (POL) [PDF – 238 KB]
    Good
    Intended population: Men who frequent gay bars
    Intervention level: Community-level
    Year published: 1997
    Author: Jeffrey A. Kelly
    Study years: 1989 – 1991
  • Positive Choice: Interactive Video Doctor [PDF – 657 KB]
    Best
    Intended population: HIV-positive clinic patients
    Intervention level: Individual-level
    Year published: 2008
    Author: Paul Gilbert
    Study years: 2003 – 2006
  • POWER [PDF – 340 KB]
    Best
    Intended population: Black men who have sex with men and women (MSMW)
    Intervention level: Individual-level
    Year published: 2016
    Author: M. Isabel Fernandez
    Study years: 2008 – 2013
  • Prime Time [PDF – 930 KB]
    Best
    Intended population: Sexually active adolescent females at elevated risk for teen pregnancy and sexually transmitted infections
    Intervention level: Individual- and group-level
    Year published: 2014
    Author: Renee E. Sieving
    Study years: 2007 – 2011
  • Project IMAGE [PDF – 231 KB]
    Good
    Intended population: Mexican and African American female adolescents with a history of sexual or physical abuse and sexually transmitted infections (STI)
    Intervention level: Group-level
    Year published: 2012
    Author: Jane D. Champion
    Study years: 2005 – 2009
  • Project LifeSkills [PDF – 232 KB]
    Best
    Intended population: Young transgender women
    Intervention level: Group-level
    Year published: 2018
    Author: Robert Garofalo
    Study years: 2012 – 2016
  • Project RISE [PDF – 915 KB]
    Best
    Intended population: Black men who have sex with men and women (MSMW)
    Intervention level: Individual-level
    Year published: 2018
    Author: Mary Milnamow
    Study years: 2010 – 2012
  • Protect & Connect (PACT) [PDF – 276 KB]
    Best
    Intended population: Men in community supervision who use drugs and their main female sex partners
    Intervention level: Couple-level
    Year published: 2019
    Author: Nabila El-Bassel
    Study years: 2013 – 2017
  • Project STYLE [PDF – 675 KB]
    Best
    Intended population: Adolescents (aged 13 – 18 years) in mental health treatment
    Intervention level: Group-level
    Year published: 2014
    Author: Larry K. Brown
    Study years: 2003 – 2008
  • Reducing the Risk Plus (RTR ) [PDF – 676 KB]
    Best
    Intended population: Adolescents
    Intervention level: Group-level
    Year published: 2014
    Author: Valerie F. Reyna
    Study years: Not reported
  • Safe in the City [PDF – 230 KB]
    Best
    Intended population: STD clinic patients
    Intervention level: Individual-level
    Year published: 2008
    Author: Lee Warner
    Study years: 2003 – 2005
  • SafeTalk [PDF – 237 KB]
    Good
    Intended population: Sexually active HIV-positive adult clinic patients
    Intervention level: Individual-level
    Year published: 2010
    Author: Carol E. Golin
    Study years: 2006 – 2009
  • Sister-to-Sister: One-on-One Skills Building [PDF – 243 KB]
    Best
    Intended population: Inner-city African American female clinic patients
    Intervention level: Individual-level
    Year published: 2007
    Author: John B. Jemmott
    Study years: 1993 – 1996
  • STRIVE [PDF – 917 KB]
    Best
    Intended population: HIV-negative injection drug users with Hepatitis C virus (HCV) infection
    Intervention level: Group-level
    Year published: 2008
    Author: Mary H. Latka
    Study years: 2002 – 2004
  • Strong African American Families-Teen (SAAF-T) [PDF – 258 KB]
    Good
    Intended population: African American adolescents living in in the rural South and their caregivers
    Intervention level: Group-level
    Year published: 2012
    Author: Steven M. Kogan
    Study years: 2007 – 2010
  • The Workshop [PDF – 303 KB] NEW 2022
    Good
    Intended population: People who use drugs (PWUD) (i.e., heroin or cocaine) and experience depressive symptoms living in an urban area with high HIV prevalence and unrecognized HIV infection
    Year published: 2017
    Author: Karen Tobin
    Study years: 2010 – 2012
    Structural components: None reported
  • Think Twice (Pilot) [PDF – 925 KB]
    Best
    Intended population: High-risk men who have sex with men (MSM)
    Intervention level: Individual-level
    Year published: 2011
    Author: Lisa A. Eaton
    Study years: 2009
  • Think Twice [PDF – 930 KB]
    Best
    Intended population: Men who have sex with men (MSM)
    Intervention level: Individual-level
    Year published: 2018
    Author: Lisa A. Eaton
    Study years: 2014 – 2015
  • Treatment Advocacy Program (TAP) [PDF – 666 KB]
    Best
    Intended population: HIV-positive sexually active men who have sex with men (MSM) clinic patients
    Intervention level: Individual-level
    Year published: 2010
    Author: David J. McKirnan
    Study years: 2004
  • Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES) [PDF – 239 KB]
    Best
    Intended population: African American and Hispanic STD clinic patients
    Intervention level: Group-level
    Year published: 1995
    Author: Lydia O’Donnell
    Study years: 1991 – 1994
  • Women Involved in Life Learning from Other Women (WiLLOW) [PDF – 227 KB]
    Best
    Intended population: Sexually-active, female clinic patients living with HIV
    Intervention level: Group-level
    Year published: 2004
    Author: Gina Wingood
    Study years: 1997 – 2002
  • WORTH [PDF – 757 KB]
    Best
    Intended population: Drug-involved, high risk female offenders under community supervision
    Intervention level: Group-level
    Year published: 2014
    Author: Nabila El-Bassel
    Study years: 2009 – 2012
  • Young Men’s Health Project [PDF – 668 KB]
    Best
    Intended population: High-risk, young gay and bisexual men
    Intervention level: Individual-level
    Year published: 2014
    Author: Jeffrey T. Parsons
    Study years: 2007 – 2010