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Intervention Research

Guided by the National HIV/AIDS Strategy for the United States, CDC provides national leadership and support for the implementation of a high-impact prevention approach to reducing new HIV infections by using combinations of scientifically proven, cost-effective, and scalable interventions and prevention strategies directed towards the most vulnerable populations in the US who are most affected by, or at greatest risk for, HIV infection. Find out more about how the Division of HIV/AIDS Prevention’s funded programs and interventions.

Effective Behavioral Interventions Evidence-based interventions (EBIs) are identified through reviewing the scientific literature and listed in the Compendium of Evidence-based Interventions. Resources on selected EBIs and other public health strategies are provided to HIV prevention partners in support of high-impact prevention.

Read more about the Compendium of EBIs

Read more about which EBIs are available

The Evidence-Based Interventions (EBIs) and Best Practices in the Compendium are identified by the CDC’s Prevention Research Synthesis (PRS) Project through a series of ongoing systematic reviews

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Replicating Effective Programs Plus The programs in REP are tested, science-based behavioral interventions with demonstrated evidence of effectiveness in reducing risky behaviors, such as unprotected sex, or in encouraging safer ones, such as using condoms and other methods of practicing safer sex.

Read more about Replicating Effective Programs Plus