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HIV/AIDS Prevention Research Synthesis Project


Prevention Research Synthesis logo with ribbons

The HIV/AIDS Prevention Research Synthesis (PRS) Project identifies evidence-based interventions (EBIs) and best practices to help HIV prevention planners and providers in the United States select interventions most appropriate for HIV prevention within their communities. These are listed in the Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention, a.k.a the “Compendium.”


The Linkage to, Retention in, and Re-engagement in HIV Care (LRC) Chapter of the Compendium highlights best practices (EBIs and Evidence-Informed Interventions) that promote linkage to, retention and re-engagement in HIV care among persons living with HIV.

The Medication Adherence (MA) Chapter of the Compendium  highlights EBIs that promote HIV medication adherence among persons living with HIV.

The Risk Reduction (RR) Chapter of the Compendium  highlights behavioral EBIs focusing on HIV-related risk reduction.

Additional PRS Project Activities

In addition to the Compendium, PRS works on other activities to improve the current knowledge and quality of science within the HIV prevention research field and improve reporting standards of non-randomized controlled trials to facilitate evidence-based public health recommendations.

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