Testing Algorithms for Fungal Pneumonias

Healthcare provider tools for community-acquired pneumonias
For Health Care Providers

Key points

  • Fungal pneumonias are often misdiagnosed or diagnosed late, leading to potentially life-threatening treatment delays.
  • In parts of the United States, common endemic community-acquired pneumonias include blastomycosis, histoplasmosis, and coccidioidomycosis (Valley fever).
  • Clinicians can use these algorithms to guide diagnostic and treatment decisions.
A doctor examining a patient. A close up shows a testing algorithm.

Overview

Blastomycosis, coccidioidomycosis (Valley fever), histoplasmosis are fungal community-acquired pneumonias (CAP) found in different parts of the United States and the world. These are also often referred to as endemic mycoses.

Guidelines exist for bacterial and viral pneumonias, leaving a gap in guidance on fungal pneumonias.

These testing algorithms can inform clinical diagnostic and treatment decisions for the three endemic mycoses.

Clinical testing guidance

These algorithms were developed by CDC, Mycoses Study Group, and Coccidioidomycosis Study Group. Infectious diseases physicians, primary care practitioners, urgent care practitioners, and epidemiologists provided consultation.

Content Source
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
About This Page
Published: May 15, 2024
Updated: October 5, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: April 25, 2024

The information on this page was last reviewed by subject matter experts to ensure accuracy.