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Increases in Drug and Opioid-Involved Overdose Deaths — United States, 2010–2015 	Increase in drug and opioid overdose deaths, United States, 2010-2015

Drug overdose deaths, including opioid overdose deaths, continue to increase in the United States, according to new data. In 2015 more than 52,000 people died from a drug overdose; of those, 63.1 percent involved an opioid. This MMWR Early Release features opioid overdoses data for 28 states and indicates that the increase in opioid overdose death rates is being driven by illicit opioids, like heroin and illicitly manufactured fentanyl, a synthetic opioid. This new report also highlights the continued need for public health and public safety to work together to prevent overdose deaths.

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An analysis of Washington prescription drug monitoring program (PDMP) data revealed that multiple provider episodes (MPEs) vary by age group and class of prescription drug. Opioids and opioid combinations had the highest number of days of overlapping prescriptions, and eight opioids had a mean daily dosage greater than 120 morphine milligram equivalents (MME). Findings indicate that MPEs, overlapping prescription, and mean daily dosages over 100 MMEs are patient risk factors to look for in PDMP data.

Maine’s PDMP data was analyzed to examine several patient risk measures for prescription drug misuse, abuse and overdose. Patients aged 35-54 had the highest rate of MPEs, and opioids were the drug class most frequently involved with MPEs. However, the rate of MPEs declined from 2010 to 2014, and this coincided with an increase in prescribing of buprenorphine, widely used in treating opioid dependence.


	Assess. Manage. Monitor. www.cdc.gov Guideline for Prescribing Opioids for Chronic Pain

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