Opioids | CDC

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In 2020, nearly 92,000 people died from drug overdoses, making it a leading cause of injury-related death in the United States. Of those deaths, nearly 75% involved a prescription or illicit opioid. Drug overdose deaths continue to increase in the United States.

strategic priorities

Framework for CDC’s Overdose Response

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Opioid Overdose Prevention Saves Lives

When we act early, we can prevent the use and misuse of drugs.

See the basics about illicit and prescription opioids including fentanyl and understanding the opioid overdose epidemic.

Opioid Data and Analysis

See information on data, research, surveillance systems, and resources related to overdose and prescribing practices, and more.

Opioid Overdose Prevention

Improve opioid prescribing, reduce exposure to opioids, prevent misuse, and treat opioid use disorder.

You can help prevent opioid overdoses and deaths

Information for Patients and Caregivers

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Information for Healthcare Providers

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Information for Healthcare Administrators

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Key Opioid Resources and Tools

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Clinical Guidance for Acute Pain

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Linking People with Opioid Use Disorder to Medication Treatment

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Rx Awareness Real Stories

Know the signs. Save a life.

Opioid Overdose Tip Card [PDF]

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Opioid Guideline Mobile App

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Evidence-Based Interventions Menu

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Opioid Rapid Response Program

Naloxone Saves Lives

Quick Links

Visit the information and resource hub

Page last reviewed: June 2, 2022

Content source: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control