Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Pneumococcal Vaccination: Summary of Who and When to Vaccinate

One of the Recommended Vaccines by Disease

There are two types of pneumococcal vaccines available in the United States:

  • Pneumococcal conjugate vaccine (PCV13 or Prevnar13®)
  • Pneumococcal polysaccharide vaccine (PPSV23 or Pneumovax23®)

CDC recommends pneumococcal vaccination for all children younger than 2 years of age and all adults 65 years or older. In certain situations, other children and adults should also receive pneumococcal vaccines. Below is more information about which pneumococcal vaccines CDC recommends by age group and medical condition (where applicable).

Children Younger than 2 Years Old

CDC recommends PCV13 for all infants as a series of 4 doses.

  • Give 1 dose at 2 months, 4 months, 6 months, and 12 through 15 months.

Children who miss their shots or start the series later should still get the vaccine. The number of doses recommended and the intervals between doses will depend on the child’s age when vaccination begins. See the Childhood/Adolescent Immunization Catch-up Schedule for additional details.

Children 2 through 4 Years Old without Certain Medical Conditions

CDC recommends PCV13 vaccination for children 2 through 4 years old who are unvaccinated or received an incomplete PCV13 series. See the Childhood/Adolescent Immunization Catch-up Schedule for additional details.

  • Give 1 dose of PCV13.

Children 2 through 5 Years Old with Certain Medical Conditions

CDC recommends pneumococcal vaccination for children 2 through 5 years old who have certain medical conditions. The tables below provide detailed information by medical condition. You can also see table 11 for additional details.

For a child with any of these conditions:
  • Chronic heart disease
  • Chronic lung disease
  • Diabetes mellitus
  • Cerebrospinal fluid leaks
  • Cochlear implant(s)
CDC recommends you:
  •  Give 2 doses of PCV13 if they are unvaccinated or received an incomplete PCV13 series with <3 doses. Give the second dose at least 8 weeks after the first.
  • Give 1 dose of PCV13 if they received 3 doses of PCV13 but none were given after 12 months of age.
  •  Give 1 dose of PPSV23 at least 8 weeks after the PCV13 series is complete.
For a child with any of these conditions:
  • Sickle cell disease or other hemoglobinopathies
  • Congenital or acquired asplenia, or splenic dysfunction
  • HIV infection
  • Chronic renal failure or nephrotic syndrome
  • Diseases associated with treatment with immunosuppressive drugs or radiation therapy, including malignant neoplasm, leukemia, lymphomas, and Hodgkin’s disease, or solid organ transplantation
  • Congenital immunodeficiency
CDC recommends you:
  • Give 2 doses of PCV13 if they are unvaccinated or received an incomplete PCV13 series with <3 doses. Give the second dose at least 8 weeks after the first.
  • Give 1 dose of PCV13 if they received 3 doses of PCV13 but none were given after 12 months of age.
  • Give 2 doses of PPSV23 after the PCV13 series is complete. Give the first dose at least 8 weeks after any prior PCV13 dose, then give the second dose of PPSV23 at least 5 years after the first.

Children 6 through 18 Years Old with Certain Medical Conditions

CDC recommends pneumococcal vaccination for children 6 through 18 years old who have certain medical conditions. The tables below provide detailed information by medical condition. See this table for additional details.

For a child with any of these conditions:
  • Cerebrospinal fluid leaks
  • Cochlear implant(s)
CDC recommends you:
  • Give 1 dose of PCV13 if they have not received any doses of PCV13. Administer PCV13 before giving any recommended doses of PPSV23.
  • Give 1 dose of PPSV23 (if not already given earlier in childhood) at least 8 weeks after PCV13.
For a child with any of these conditions:
  • Sickle cell disease or other hemoglobinopathies
  • Congenital or acquired asplenia, or splenic dysfunction
  • HIV infection
  • Chronic renal failure or nephrotic syndrome
  • Diseases associated with treatment with immunosuppressive drugs or radiation therapy, including malignant neoplasm, leukemia, lymphomas, and Hodgkin’s disease, or solid organ transplantation
  • Congenital immunodeficiency
CDC recommends you:
  • Give 1 dose of PCV13 if they have not received any doses of PCV13. Administer PCV13 before giving any recommended doses of PPSV23.
  • Ensure the child receives 2 doses of PPSV23. The first dose of PPSV23 should be given at least 8 weeks after any prior PCV13 dose, then the second dose of PPSV23 should be given at least 5 years after the first.
For a child with any of these conditions:
  • Chronic heart disease
  • Chronic lung disease
  • Diabetes mellitus
  • Alcoholism
  • Chronic liver disease
  • Cigarette smoking
CDC recommends you:
  • Give 1 dose of PPSV23 (if not already given earlier in childhood).

Adults 19 through 64 Years

CDC recommends pneumococcal vaccination for adults 19 through 64 years old who have certain medical conditions or who smoke. The tables below provide detailed information by medical condition and smoking status. See Pneumococcal Vaccine Timing for Adults for additional details.

For anyone with any of the conditions listed below who has not previously received the recommended pneumococcal vaccines:
  • Cerebrospinal fluid leaks
  • Cochlear implant(s)
CDC recommends you:
  • Give 1 dose of PCV13 and 1 dose of PPSV23. Administer PCV13 first, then give the PPSV23 dose at least 8 weeks later.
For anyone with any of the conditions listed below who has not previously received the recommended pneumococcal vaccines:
  • Sickle cell disease or other hemoglobinopathies
  • Congenital or acquired asplenia
  • Congenital or acquired immunodeficiency
  • HIV infection
  • Chronic renal failure or nephrotic syndrome
  • Leukemia or lymphoma
  • Hodgkin’s disease
  • Generalized malignancy
  • Iatrogenic immunosuppression (diseases requiring treatment with immunosuppressive drugs, including long-term systemic corticosteroids and radiation therapy)
  • Solid organ transplantation
  • Multiple myeloma
CDC recommends you:
  • Give 1 dose of PCV13 and 2 doses of PPSV23. Administer PCV13 first, then give the first PPSV23 dose at least 8 weeks later. Give the second dose of PPSV23 at least 5 years after the first.
For anyone who smokes and has not previously received the recommended pneumococcal vaccine
CDC recommends you:
  • Give 1 dose of PPSV23.
For anyone with any of the conditions listed below who has not previously received the recommended pneumococcal vaccine:
  • Alcoholism
  • Chronic heart disease
  • Chronic liver disease
  • Chronic lung disease
  • Diabetes mellitus
CDC recommends you:
  • Give 1 dose of PPSV23.

Adults 65 Years or Older

CDC recommends pneumococcal vaccination for all adults 65 years or older. See Pneumococcal Vaccine Timing for Adults [4 pages] for additional details.

  • Give 1 dose of PCV13 to all adults 65 years or older who have not previously received a dose.
  • Give 1 dose of PPSV23 to all adults 65 years or older at least 1 year after any prior PCV13 dose and at least 5 years after any prior PPSV23 dose.
    • Adults who received one or two doses of PPSV23 before age 65 should receive one final dose of the vaccine at age 65 or older.

 Top of Page

TOP