Vaccination can help prevent typhoid fever. CDC recommends vaccination for people traveling to places where typhoid fever is common, such as South Asia, especially India, Pakistan, or Bangladesh.
Visit a doctor or travel clinic to discuss options.
Two typhoid fever vaccines are available in the United States.
- Oral vaccine: Can be given to people at least 6 years old. It consists of four pills taken every other day and should be finished at least 1 week before travel.
- Injectable vaccine: Can be given to people at least 2 years old and should be given at least 2 weeks before travel.
Typhoid vaccines are not 100% effective. Always practice safe eating and drinking habits to help prevent infection.
Typhoid vaccines lose effectiveness over time. The injectable vaccine requires a booster every 2 years, and the oral vaccine requires a booster every 5 years. If you were vaccinated in the past, ask your doctor if it is time for a booster vaccination. Taking antibiotics will not prevent typhoid fever; they only help treat it.
Basic Information on Typhoid Vaccines Available in the United States
Please note: In December 2020, the maker of the oral typhoid fever vaccine (Ty21a) will temporarily stop making and selling it. This vaccine may be in limited supply or unavailable.
|Abbreviated vaccine name (brand name, manufacturer)||How given||Number of doses recommended||When taken||How long to complete immunization before travel||Minimum age for vaccination||Booster needed|
|Ty21a (Vivotif, Emergent BioSolutions)||1 capsule by mouth||4||Every other day||1 week||6 years||Every 5 years|
|ViCPS (Typhim Vi, Sanofi Pasteur)||Injection||1||Once||2 weeks||2 years||Every 2 years|
See Vaccine Information Statements (VIS) for more information.
- Find out who should get the typhoid fever vaccine and when >
- Read the typhoid fever and paratyphoid fever chapter in CDC Health Information for International Travel >
- Get information and prevention tips on CDC’s Traveler’s Health site >
- Learn about symptoms, prevention, and treatment by reading CDC’s Typhoid and Paratyphoid Fever Factsheet > pdf icon[PDF – 159 KB]
- Reduce your chances of getting sick while traveling with these safe eating and drinking tips >