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Sexually Transmitted Infections Treatment Guidelines, 2021

CDC’s Sexually Transmitted Infections (STI) Treatment Guidelines, 2021 provides current evidence-based prevention, diagnostic and treatment recommendations that replace the 2015 guidance. The recommendations are intended to be a source for clinical guidance. Healthcare providers should always assess patients based on their clinical circumstances and local burden.

Browse Guidelines Online

View the full STI Treatment Guidelines.


Access print-friendly versions of the wall chart, pocket guide, and guidelines.

National Network of STD Prevention Training Centers

Explore STD trainings, technical assistance, clinical consultation services, and more.

Recommendations for Providing Quality STD Clinical Services

Learn about recommendations and tools to help healthcare settings improve STD care services.

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