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Provider Resources

STI Treatment Guide Mobile App banner
STI Treatment (Tx) Guide Mobile App

The new app offers quick and easy access to streamlined STI prevention, diagnostic, and treatment recommendations. The user-friendly interface includes more clinical care guidance, sexual history resources, patient materials, and other features to assist with patient management. Download the free app for Apple and Android mobile devices.

Download in the App Store Get it on Google Play
Wall Chart
Wall Chart[PDF - 330 KB]

An 18×24 at-a-glance poster of recommended STI regimens.

Pocket Guide
Pocket Guide[PDF - 390 KB]

A handy pocket guide outlining recommended STI regimens.

PDF Version
Print Version[PDF - 4 MB]

Download the full 2021 STI Treatment Guidelines.

Please note: the wall chart is an 18×24 poster and not suitable for at-home printing. Limited print copies of the above products are available from CDC-INFO on Demand.

Other Resources

Mycoplasma genitalium (Mgen) Treatment Failure Registry – Healthcare providers and health departments can report Mgen treatment failures to the CDC. (December 12, 2022)

Suspected Gonorrhea Treatment Failure Consultation Form – Healthcare providers and health departments can report suspected gonorrhea cephalosporin treatment failure or any N. gonorrhoeae specimen with decreased cephalosporin susceptibility to the CDC. (December 12, 2022)

Medscape Commentary – CDC experts highlight five key changes to know about the 2021 STI Treatment Guidelines. (October 12, 2022)

National STD Curriculum – An online modular learning experience that helps users learn how to manage STDs. Free CME/CNE available.

STD Clinical Consultation Network – A free STD consultation service for healthcare providers provided by the National Network of STD Clinical Prevention Training Centers (NNPTC).

STI Treatment Guidelines Questions and Answers – CDC experts address questions and comments from partners, stakeholders, and providers about the updated guidelines. (December 18, 2020)

A Guide for Taking a Sexual History – This booklet provides guidance on how to discuss sexual health issues with patients. Available on CDC-INFO on Demand.

Drug and Diagnostic Test Shortages – Up-to-date information about national drug shortages and diagnostic testing kits.

Syphilis Pocket Guide for Providers – A booklet with details on syphilis diagnosis, treatment, and prevention. (November 30, 2017)

The Diagnosis, Management and Prevention of Syphilis: An Update and Review – Clinical guidance for diagnosing and managing syphilis. This document reflects content from the 2015 CDC STD Treatment Guidelines. This is a product of the NYC Department of Health and Mental Hygiene Bureau of Sexually Transmitted Infections and the NYC STD Prevention Training Center.  (March 2019)

Prenatal Syphilis Screening Laws by State – Outlines state statutory and regulatory language regarding prenatal syphilis screening in the United States.

Expedited Partner Therapy – Information, guidance, and resources to effective treat and manage patients diagnosed with an STD and their sex partner(s).

STD Clinical Slides – STI clinical slides depicting disease manifestations and laboratory images of the organism.

Videos & Podcasts – Brief videos and audio podcasts about STIs featuring CDC staff.

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