Immunization Information Systems (IISs)

Immunization information systems (IISs) are population-based, computerized databases that record all vaccine doses administered by participating clinicians to patients within a given area.  IISs can provide immunization histories and aggregate immunization data, and can guide public health action to improve vaccination rates and reduce vaccine-preventable diseases.

The Community Preventive Services Task Force recommends using IISs, which are effective in increasing vaccination rates through their capacities to:

  • Create or support interventions such as reminder/recall, AFIX, and provider reminders
  • Determine patient vaccination status
  • Inform vaccination coverage assessments, missed vaccination opportunities, invalid dose administration, and vaccination coverage disparities
  • Facilitate vaccine inventory management and accountability

For more information on IISs, visit the Immunization Information Systems website, or contact