Resources & Publications


Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021

These are the first comprehensive clinical care guidelines for botulism. They include

  • Best practices for diagnosing, monitoring, and treating botulism, including during outbreaks
  • Special considerations for infants, children, and people who are pregnant or breastfeeding
  • Recommendations for supportive care, including psychosocial support for patients and family members
Illustration of a female with botulism

“Botulism,” a CDC-sponsored supplement to Clinical Infectious Diseases

The supplement includes six systematic reviews and other articles that provided the evidence base for the clinical guidelines. Contents include reviews and articles on

  • Clinical presentation
  • Effectiveness of antitoxin
  • Antitoxin adverse reactions
  • Outbreaks
  • And more
Illustration of a male with botulism

Preparing and Administrating Heptavalent Antitoxin for the Treatment of Botulism

CDC created this video to guide healthcare professionals on preparing and administering antitoxin for the treatment of botulism. Refer to the FDA package insert for complete information.

Other Resources