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About the Vaccine

One of the Recommended Vaccines

Vaccine Composition and Dosage

The two rotavirus vaccines that are currently licensed for use in infants in the United States have a similar composition.

  • RotaTeq® (RV5)
    • Licensed in 2006
    • Administered in three doses at 2 months, 4 months, and 6 months of age
    • Package insert for RotaTeq®[13 pages]provides dosage forms and strengths as well as administration guidance.
  • Rotarix® (RV1)

Both vaccines are given orally, by putting drops in the infant’s mouth. The vaccine should not be injected.

 

Vaccine Effectiveness and Duration of Protection

RotaTeq® (RV5)

  • In large clinical trials, RotaTeq®demonstrated 98% protection against severe rotavirus gastroenteritis (fever, vomiting, diarrhea, and changes in behavior), and 74% protection against gastroenteritis of any severity (inflammation of the stomach and intestine) caused by rotavirus through the first rotavirus season (December through June) after vaccination.
  • Also, infants who were vaccinated with RotaTeq®were 94% less likely to visit an emergency room and 96% less likely to be hospitalized through the first 2 years after vaccination.

For more information on RotaTeq, visit the manufacturer’s site or the U.S. Food and Drug Administration (FDA) information page.

Rotarix® (RV1)

  • Two clinical trials found Rotarix®to have 85 to 96% protection against severe rotavirus gastroenteritis through two rotavirus seasons (December through June).
  • One study found Rotarix®to be 96% effective in reducing hospitalizations through two rotavirus seasons.

For more information on Rotarix, visit the manufacturer’s site or the U.S. Food and Drug Administration (FDA) information page.

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