Storage and Handling for Meningococcal Vaccines

Proper vaccine storage and handling practices play an important role in protecting individuals and communities from vaccine-preventable diseases. For general recommendations and guidance, see Vaccine Storage and Handling. Provided below is guidance specific to meningococcal vaccines.


  • Store meningococcal vaccines refrigerated between 2°C and 8°C (36°F and 46°F).
  • Do not freeze vaccine or diluents, or expose to freezing temperatures. If the vaccine has been exposed to inappropriate conditions/temperatures or handled improperly:
    • Store the vaccine at the appropriate temperature
    • Isolate from other vaccines
    • Mark “Do NOT Use”
    • Consult the vaccine manufacturer and/or your state or local immunization program for guidance


  • Store meningococcal vaccines in the original packaging.
    • For meningococcal vaccines that require reconstitution (Menveo®, Penbraya™), store diluent and vaccine (which are packaged together) together in the refrigerator.


  • For meningococcal vaccines that require reconstitution (Menveo®, Penbraya™), do NOT use if the reconstituted vaccine cannot be resuspended with thorough agitation.
    • Only reconstitute diluents for the vaccine (Menveo®, Penbraya™) which contain antigen, with the corresponding lyophilized vaccine provided by the manufacturer.
    • Never use stock vials of normal saline to reconstitute these vaccines.


  • Discard vaccine vials and syringes using proper medical waste disposal procedures.