Pediculosis Pubis

Adolescents and Adults
Recommended Regimen

Permethrin 1% cream rinse applied to affected areas and washed off after 10 minutes 

OR 

Pyrethrin with piperonyl butoxide applied to the affected area and washed off after 10 minutes 

Alternative Regimen

Malathion 0.5% lotion applied to affected areas and washed off after 8–12 hours 

OR 

Ivermectin 250 μg/kg body weight orally, repeated in 7–14 days 

Persons with HIV
Recommended Regimen

Persons who have pediculosis pubis and HIV infection should receive the same treatment regimen as those who do not have HIV. 

Alternative Regimen

None

Pregnant Women
Recommended Regimen

Existing data from human participants demonstrate that pregnant and lactating women should be treated with either permethrin or pyrethrin with piperonyl butoxide. Because no teratogenicity or toxicity attributable to ivermectin has been observed during human pregnancy experience, ivermectin is classified as “human data suggest low risk” during pregnancy and probably compatible with breastfeeding.  

Alternative Regimen

None

Page last reviewed: July 16, 2021
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