Chlamydia (CT)

Adolescents and Adults
Recommended Regimen

Doxycycline 100 mg orally 2 times/day for 7 days 

Alternative Regimen

Azithromycin 1 g orally in a single dose 

OR 

Levofloxacin 500 mg orally once daily for 7 days 

In Pregnancy
Recommended Regimen

Azithromycin 1 g orally in a single dose 

Alternative Regimen

Amoxicillin 500 mg orally 3 times/day for 7 days 

Persons Living with HIV
Recommended Regimen

Persons who have chlamydia and HIV infection should receive the same treatment regimen as those who do not have HIV.

Alternative Regimen

None

Infants and Children (4 weeks – 12 years)
Recommended Regimen

For infants and children weighing <45 kg: Erythromycin base or ethyl succinate 50 mg/kg body weight/day orally divided into 4 doses daily for 14 days. 

Data are limited regarding the effectiveness and optimal dose of azithromycin for treating chlamydial infection among infants and children weighing <45 kg. 

For children weighing ≥45 kg but aged <8: Azithromycin 1 g orally in a single dose 

For children aged ≥8 years: Azithromycin 1 g orally in a single dose 

OR 

Doxycycline 100 mg orally 2 times/day for 7 days 

Alternative Regimen

None

Neonates (up to 4 weeks)
Recommended Regimen

Erythromycin base or ethyl succinate 50 mg/kg body weight/day orally, divided into 4 doses daily for 14 days* 

*An association between oral erythromycin and azithromycin and infantile hypertrophic pyloric stenosis (IHPS) has been reported among infants aged <6 weeks. Infants treated with either of these antimicrobials should be followed for IHPS signs and symptoms 

Alternative Regimen

None

Infant Pneumonia caused by C. trachomatis
Recommended Regimen

Erythromycin base or ethyl succinate 50 mg/kg body weight/day orally, divided into 4 doses daily for 14 days 

Alternative Regimen

Azithromycin suspension 20 mg/kg body weight/day orally, 1 dose daily for 3  days 

Page last reviewed: July 16, 2021
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